版本2.7.1 ---------------------------------------------------------修复了o parsemetafromgtffile改进(模棱两可的函数调用,fasta描述符中的空格)o brainarray摘要到多个基因/探针的地图新功能o此软件包为Affymetrix HTA 2.0阵列提供了支持2.5.8版本的更改---------------------------------------------------------------------------------------------新功能o此软件包现在提供了“通用”功能,用于提高任何类型的基因表达数据。这些值可以作为向量或表达式对象输入。这意味着来自Illumina Beadchip微阵列或任何其他类型的微阵列的数据可以相对轻松地归一化。通过与GeoQuery软件包集成,可以轻松地将GEO的所有预处理数据集归一化。o此软件包现在使用SVA软件包中的战斗功能,使其易于调整基因表达数据以获得批处理效果。这可以针对任何类型的表达数据完成。o现在可以将RNA序列数据输入为矩阵文件和/或输入数据文件中存在标头的位置。注释o scan_twocolor和upc_twocolor函数已更改。 They now return ExpressionSet objects. o The SCAN_TwoColor and UPC_TwoColor methods now add an integer suffix to each probe for which there is a duplicate name. o The UPC_RNASeq function now also returns an ExpressionSet object. o A bug was fixed in which UPC_RNASeq returned NA values if there was no entry in the annotation file. CHANGES IN VERSION 2.2.8 ------------------------- NEW FEATURES o Ability to download microarray data directly from Gene Expression Omnibus and normalize the files in a single command. o Alternate functions (SCANfast and UPCfast) for performing SCAN and UPC normalization that use fewer probes and thus execute in ~60% less time. o Ability to execute normalize multiple .CEL files in parallel either across multiple cores on a single computer or across multiple computers on a cluster. o Ability to generate RNA-Seq annotation files to be used with the UPC_RNASeq function from GTF/FASTA source files. o Ability to download and install BrainArray packages via an R function. o Improved support for Affymetrix exon arrays. o Improved support for Affymetrix HT_HG-U133A early access exon arrays. OTHER o Various improvements and clarifications to the docs.