1.5.1版本新功能的变化,修复bug相关coverage_norm(),确保区域用于正常化覆盖seqlevels相同输入连接。1.3.8版本新功能的变化,修复bug相关pkgdown:: deploy_to_branch ()。1.3.6版新功能的变化,添加功能注释连接gene_name /符号使用EnsDb计入junction_annot ()。1.3.2版本新功能的变化,修复bug在plot_sashimi()和启用可视化生结项。1.1.1版本新特性的变化,使用testthat版3和parrallel运行的测试。0.99.2版本新特性的变化——文档合并到一个页面连接,覆盖和异常处理功能,减少运行时的roxygen例子。0.99.1版本新特性的变化,改变outlier_detect()为接口使用蛇怪到python取代网状。0.99.0版本新特性的变化——dasper转换为使用biocthis Bioconductor-friendly格式。——添加junction_load(),它从RNA-sequencing生结数据装入一个RangedSummarizedExperiment对象。包含一个选项允许用户指定的控制连接下载。 - Added junction_annot(), which uses information from reference annotation and the strand of a junction to classify junctions as "annotated", "novel_acceptor", "novel_donor", "novel_exon_skip", "novel_combo", "ambig_gene" and "unannotated". - Added junction_filter(), which filters junctions by their count, width, annotation or if they overlap a set of user-defined regions. - Added junction_norm(), which normalises raw junction counts (into a proportion-spliced-in) by dividing the counts of each junction by the total number of counts in it's associated cluster. - Added junction_process(), a wrapper function for all "junction_" prefixed functions except junction_load(). - Added junction_score(), which scores patient junctions based on the extent their counts deviate from a control count distribution. - Added coverage_norm(), which will load and normalise coverage for exonic/intronic regions corresponding to each junction. - Added coverage_score(), which scores coverage associated with each junction based on it's deviation from control coverage distributions. - Added coverage_process(), a wrapper function for all "coverage_" prefixed functions. - Added outlier_detect(), which uses the junction scores and coverage scores as input into an unsupervised outlier detection algorithm to find the most outlier-looking junctions in each sample. - Added outlier_aggregate(), which aggregates the junction-level outlier data to a cluster-level. - Added outlier_process(), a wrapper function for all "outlier_" prefixed functions. - Added plot_sashimi(), which enables the visualisation of junction data across genes/transcripts or regions of interest.