在2.7.1版本的变化-------------------------修复o ParseMetaFromGtfFile改进(模糊函数调用,FASTA描述符中的空格)o当探针映射到多个基因/探针集时,BrainArray总结新功能o这个包提供了对Affymetrix HTA 2.0数组的支持2.5.8版本的变化-------------------------新功能o这个包现在提供了UPC规范任何类型的基因表达数据的“通用”函数。这些值可以作为向量或ExpressionSet对象输入。这意味着来自Illumina BeadChip微阵列或任何其他类型的微阵列的数据可以相对容易地进行UPC标准化。通过与GEOquery包集成,可以很容易地UPC规范化来自GEO的任何预处理数据集。o这个包现在使用来自sva包的ComBat函数,使其易于调整基因表达数据的批处理效果。这可以用于任何类型的表达式数据。o rna -测序数据现在可以作为矩阵文件和/或在输入数据文件中存在头的地方输入。注意:scan_twocololor和upc_twocololor函数已经改变。它们现在返回ExpressionSet对象。o SCAN_TwoColor和UPC_TwoColor方法现在为每个有重复名称的探测添加一个整数后缀。 o The UPC_RNASeq function now also returns an ExpressionSet object. o A bug was fixed in which UPC_RNASeq returned NA values if there was no entry in the annotation file. CHANGES IN VERSION 2.2.8 ------------------------- NEW FEATURES o Ability to download microarray data directly from Gene Expression Omnibus and normalize the files in a single command. o Alternate functions (SCANfast and UPCfast) for performing SCAN and UPC normalization that use fewer probes and thus execute in ~60% less time. o Ability to execute normalize multiple .CEL files in parallel either across multiple cores on a single computer or across multiple computers on a cluster. o Ability to generate RNA-Seq annotation files to be used with the UPC_RNASeq function from GTF/FASTA source files. o Ability to download and install BrainArray packages via an R function. o Improved support for Affymetrix exon arrays. o Improved support for Affymetrix HT_HG-U133A early access exon arrays. OTHER o Various improvements and clarifications to the docs.