版本3.7.1的变化------------------------用户可见的变化o添加了精确到小数点后2位的总分。参见方法“population()”和“defaultPopulation()”。o添加元数据标签和组注释自动操作的分数。参见方法“gscoresstag()”和“gscoresGroup()”。o增加了得分站点总数的元数据。参见方法'nsites()'。3.6.0版本中的变化------------------------用户可见的变化o增加了通过GScores对象和'citation()'方法可用的引文元数据。版本3.5.0更改------------------------用户可见更改o支持访问此注释包的类定义和方法已从VariantFiltering包移动到GenomicScores包。o在<= 3.4版本中,缺失的phastCons得分被编码为0,现在被编码为NAs。版本3.2.0的变化------------------------用户可见的变化o在VariantFiltering包scores()函数中的更新,可以在基因组间隔上以10倍快的速度检索平均phastCons分数。 CHANGES IN VERSION 3.1.0 ------------------------ USER VISIBLE CHANGES o Updated phastCons scores to the UCSC available data on March 2015 o Individual files storing phastCons scores per chromosome within the 'extdata' directory of the package are now stored and loaded using the saveRDS() and readRDS() functions instead of classical save() and load(). Corresponding filenames have now an '.rds' extension and the chromosome name is written now at the end of the filename, right before '.rds'. CHANGES IN VERSION 3.0.0 ------------------------ USER VISIBLE CHANGES o Updated phastCons scores to the UCSC available data on October 2014 o Instead loading in main memory the set of phastCons scores for the entire human genome, they are now stored separetely by chromosome and they are loaded and cached into main memory as different chromosomes get accessed to reduce the memory footprint at package loading time. Caching may be disabled, and thus memory footprint minimized, setting a new argument 'caching=FALSE' in the 'scores()' function, at the cost of slowing down multiple calls to the 'scores()' function. CHANGES IN VERSION 0.99.1 ------------------------- USER VISIBLE CHANGES o Submission of the first version to the Bioconductor project. (start date: 15 April, 2014)