## try http:// if https:// URLs are not supported source("//www.anjoumacpherson.com/biocLite.R") biocLite("multtest")

DOI:10.18129/B9.bioc.multtest

Resampling-based multiple hypothesis testing

Bioconductor version: Release (3.5)

Non-parametric bootstrap and permutation resampling-based multiple testing procedures (including empirical Bayes methods) for controlling the family-wise error rate (FWER), generalized family-wise error rate (gFWER), tail probability of the proportion of false positives (TPPFP), and false discovery rate (FDR). Several choices of bootstrap-based null distribution are implemented (centered, centered and scaled, quantile-transformed). Single-step and step-wise methods are available. Tests based on a variety of t- and F-statistics (including t-statistics based on regression parameters from linear and survival models as well as those based on correlation parameters) are included. When probing hypotheses with t-statistics, users may also select a potentially faster null distribution which is multivariate normal with mean zero and variance covariance matrix derived from the vector influence function. Results are reported in terms of adjusted p-values, confidence regions and test statistic cutoffs. The procedures are directly applicable to identifying differentially expressed genes in DNA microarray experiments.

Author: Katherine S. Pollard, Houston N. Gilbert, Yongchao Ge, Sandra Taylor, Sandrine Dudoit

Maintainer: Katherine S. Pollard

Installation

To install this package, start R and enter:

## try http:// if https:// URLs are not supported source("//www.anjoumacpherson.com/biocLite.R") biocLite("multtest")

Documentation

PDF		Reference Manual

Details

biocViews	DifferentialExpression,Microarray,MultipleComparison,Software
Version	2.32.0
In Bioconductor since	BioC 1.6 (R-2.1) or earlier (> 12.5 years)
License	LGPL
Depends	R (>= 2.10), methods,BiocGenerics,Biobase
Imports	survival,MASS, stats4
LinkingTo
Suggests	snow
SystemRequirements
Enhances
URL
Depends On Me	a4Base,aCGH,BicARE,iPAC,KCsmart,LMGene,PREDA,rain,REDseq,SAGx,siggenes,webbioc
Imports Me	ABarray,aCGH,adSplit,anota,ChIPpeakAnno,GeneSelector,IsoGeneGUI,mAPKL,metabomxtr,nethet,OCplus,phyloseq,REDseq,RTopper,synapter,webbioc,xcms
Suggests Me	annaffy,BiocCaseStudies,ecolitk,factDesign,GeneSelector,GGtools,GOstats,gQTLstats,GSEAlm,maigesPack,MmPalateMiRNA,oneChannelGUI,pcot2,ropls,topGO
Build Report

Package Archives

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Source Package	multtest_2.32.0.tar.gz
Windows Binary	multtest_2.32.0.zip(32- & 64-bit)
Mac OS X 10.11 (El Capitan)	multtest_2.32.0.tgz
Source Repository	git clone https://git.bioconductor.org/packages/multtest
Package Short Url	//www.anjoumacpherson.com/packages/multtest/
Package Downloads Report	Download Stats