变化在3.12版本中BUG报告,错误的重复数据删除的情况下,验证加。问题:623 -修复lollipopPlot2重复域标签。问题:614 -修复拷贝数在coBarPlot标签和着色。问题:609 -修复着色问题注释在oncoplot R < 4.0。问题:599增强-更新TCGA三甲。所有变体MC3结果限制和协调安捷伦35.8 MB捕获工具。看到了什么? tcgaCompare细节。问题:612 -添加SIMC1蛋白质域数据库。问题:616 -添加sampleOrder1和coOncoplot sampleOrder2参数。问题:592 -添加gene_mar coOncoplot outer_mar参数。 Issue: 260 - Added sample size warning messages to mafCompare. Issue: 602 - Added cohortFontSize and axisFontSize to tcgaCompare NEW FUNCTIONS - Added filterMaf function. DEPRECATED - signatureEnrichment will be deprecated in future. Currently kept for legacy purpose with a warning message. Issue: 607 615 Changes in version 2.6.05 BUG REPORTS - mafSurvival Remove non functional fn argument. Issue: 660 - OncogenicPathways zero entries bug and correct documentation. Issue: 656 - plotApobecDiff y-axis limits. Issue: 642 629 - Rainfallplot arrowhead bug. Issue: 628 629 ENHANCEMENTS - Improve clinicalEnrichment odd-ratio interpretation. Issue: 633 In earlier versions, odds-ratio indicated the odds of observing WT in the group of interest compared to Mutant. From this update, odds-ratio indicate the odds of observing mutant in the group of interest compared to wild-type. This way is much intuitive and easier interpret. See issue 633 for details. P-values and other details are unaffected. - Changes in how Multi_Hit are reported. By default two distinct types of mutations in the same gene or same patient were classified as Multi_Hit (e.g; Missense + Splice_Site = Multi_Hit; Missense + Missense = Missense). This update onward, regardless of type of mutations, if there are >1 mutations in the same gene of same patient, they are classified as Multi_Hit (e.g; Missense + Splice_Site = Multi_Hit; Missense + Missense = Multi_Hit). Issue: 347 347