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ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 451.33 659.69 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 416.42 688.20 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 475.83 622.51 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 472.25 744.15 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 493.42 718.11 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 462.09 662.52 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 313.95 670.05 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 420.03 715.21 Tm (IPF) Tj ET 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 317.06 667.15 m 556.45 677.02 l S 0.75 w [ 3.00 5.00] 0 d 317.06 681.28 m 556.45 691.14 l S Q q 19.48 420.24 258.54 154.28 re W n Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 49.71 420.24 m 247.18 420.24 l S 49.71 420.24 m 49.71 417.86 l S 99.08 420.24 m 99.08 417.86 l S 148.45 420.24 m 148.45 417.86 l S 197.81 420.24 m 197.81 417.86 l S 247.18 420.24 m 247.18 417.86 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 4.00 0.00 -0.00 4.00 46.93 411.68 Tm (7.6) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 96.30 411.68 Tm (7.8) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 145.67 411.68 Tm (8.0) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 195.03 411.68 Tm (8.2) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 244.40 411.68 Tm (8.4) Tj ET 19.48 438.74 m 19.48 567.64 l S 19.48 438.74 m 17.11 438.74 l S 19.48 460.22 m 17.11 460.22 l S 19.48 481.71 m 17.11 481.71 l S 19.48 503.19 m 17.11 503.19 l S 19.48 524.67 m 17.11 524.67 l S 19.48 546.16 m 17.11 546.16 l S 19.48 567.64 m 17.11 567.64 l S BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 435.96 Tm (7.6) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 457.44 Tm (7.8) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 478.93 Tm (8.0) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 500.41 Tm (8.2) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 521.89 Tm (8.4) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 543.38 Tm (8.6) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 564.86 Tm (8.8) Tj ET 19.48 420.24 m 278.02 420.24 l 278.02 574.52 l 19.48 574.52 l 19.48 420.24 l S Q q 0.00 396.00 288.00 198.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 5.00 0.00 -0.00 5.00 131.52 582.46 Tm (NM_000016_at) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 140.97 402.18 Tm (dataT[i, ]) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 4.28 489.48 Tm (dataP[i, ]) Tj ET Q q 19.48 420.24 258.54 154.28 re W n BT 0.000 0.000 0.000 rg /F2 1 Tf 4.00 0.00 -0.00 4.00 258.97 521.74 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 217.82 513.96 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 162.60 497.61 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 251.10 492.12 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 92.78 447.39 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 123.54 567.37 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 188.35 526.70 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 147.42 485.56 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 100.76 479.50 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 113.94 519.44 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 148.07 472.90 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 214.06 482.98 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 179.19 435.44 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 265.33 532.65 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 96.07 504.63 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 76.85 424.51 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 39.99 443.40 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 192.51 488.88 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 25.95 428.26 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 83.79 515.61 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 177.50 429.74 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 110.57 489.03 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 246.61 433.87 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 227.52 501.08 Tm (IPF) Tj ET 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 29.06 483.14 m 268.45 514.78 l S 0.75 w [ 3.00 5.00] 0 d 29.06 454.83 m 268.45 486.47 l S Q q 307.48 420.24 258.54 154.28 re W n Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 347.62 420.24 m 526.60 420.24 l S 347.62 420.24 m 347.62 417.86 l S 392.37 420.24 m 392.37 417.86 l S 437.11 420.24 m 437.11 417.86 l S 481.86 420.24 m 481.86 417.86 l S 526.60 420.24 m 526.60 417.86 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 4.00 0.00 -0.00 4.00 344.84 411.68 Tm (5.8) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 389.59 411.68 Tm (6.0) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 434.33 411.68 Tm (6.2) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 479.08 411.68 Tm (6.4) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 523.82 411.68 Tm (6.6) Tj ET 307.48 442.53 m 307.48 561.21 l S 307.48 442.53 m 305.11 442.53 l S 307.48 466.27 m 305.11 466.27 l S 307.48 490.00 m 305.11 490.00 l S 307.48 513.74 m 305.11 513.74 l S 307.48 537.47 m 305.11 537.47 l S 307.48 561.21 m 305.11 561.21 l S BT /F2 1 Tf 0.00 4.00 -4.00 0.00 301.78 439.75 Tm (6.0) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 301.78 463.49 Tm (6.2) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 301.78 487.22 Tm (6.4) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 301.78 510.96 Tm (6.6) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 301.78 534.69 Tm (6.8) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 301.78 558.43 Tm (7.0) Tj ET 307.48 420.24 m 566.02 420.24 l 566.02 574.52 l 307.48 574.52 l 307.48 420.24 l S Q q 288.00 396.00 288.00 198.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 5.00 0.00 -0.00 5.00 419.52 582.46 Tm (NM_000017_at) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 428.97 402.18 Tm (dataT[i, ]) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 292.28 489.48 Tm (dataP[i, ]) Tj ET Q q 307.48 420.24 258.54 154.28 re W n BT 0.000 0.000 0.000 rg /F2 1 Tf 4.00 0.00 -0.00 4.00 313.28 471.05 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 393.68 435.99 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 402.38 567.37 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 395.61 470.43 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 432.41 514.98 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 376.05 424.51 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 484.62 513.04 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 479.96 506.73 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 474.89 477.88 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 459.04 489.53 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 371.73 484.59 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 435.10 438.56 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 445.43 528.13 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 392.72 495.95 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 361.68 461.58 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 469.95 529.87 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 505.61 523.85 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 457.70 467.67 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 481.97 452.30 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 514.87 531.03 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 501.89 498.46 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 553.33 563.49 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 411.73 565.02 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 353.13 547.51 Tm (IPF) Tj ET 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 317.06 468.33 m 556.45 504.82 l S 0.75 w [ 3.00 5.00] 0 d 317.06 493.80 m 556.45 530.29 l S Q q 19.48 222.24 258.54 154.28 re W n Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 47.03 222.24 m 275.37 222.24 l S 47.03 222.24 m 47.03 219.86 l S 92.70 222.24 m 92.70 219.86 l S 138.36 222.24 m 138.36 219.86 l S 184.03 222.24 m 184.03 219.86 l S 229.70 222.24 m 229.70 219.86 l S 275.37 222.24 m 275.37 219.86 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 4.00 0.00 -0.00 4.00 44.25 213.68 Tm (9.6) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 89.92 213.68 Tm (9.8) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 134.47 213.68 Tm (10.0) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 180.14 213.68 Tm (10.2) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 225.81 213.68 Tm (10.4) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 271.47 213.68 Tm (10.6) Tj ET 19.48 223.72 m 19.48 374.11 l S 19.48 223.72 m 17.11 223.72 l S 19.48 261.32 m 17.11 261.32 l S 19.48 298.91 m 17.11 298.91 l S 19.48 336.51 m 17.11 336.51 l S 19.48 374.11 m 17.11 374.11 l S BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 220.94 Tm (9.0) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 258.54 Tm (9.5) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 295.02 Tm (10.0) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 332.62 Tm (10.5) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 13.78 370.21 Tm (11.0) Tj ET 19.48 222.24 m 278.02 222.24 l 278.02 376.52 l 19.48 376.52 l 19.48 222.24 l S Q q 0.00 198.00 288.00 198.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 5.00 0.00 -0.00 5.00 131.52 384.46 Tm (NM_000018_at) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 140.97 204.18 Tm (dataT[i, ]) Tj ET BT /F2 1 Tf 0.00 4.00 -4.00 0.00 4.28 291.48 Tm (dataP[i, ]) Tj ET Q q 19.48 222.24 258.54 154.28 re W n BT 0.000 0.000 0.000 rg /F2 1 Tf 4.00 0.00 -0.00 4.00 248.68 312.50 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 213.50 298.11 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 108.12 311.02 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 73.50 282.78 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 232.11 273.71 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 214.00 243.03 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 144.47 284.43 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 196.82 287.38 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 168.66 308.82 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 207.90 286.66 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 25.28 226.51 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 61.95 251.74 Tm (HLF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 107.38 322.49 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 105.40 262.82 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 128.64 359.03 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 194.27 357.45 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 241.41 341.29 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 136.76 300.09 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 186.75 342.49 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 171.72 322.80 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 165.20 322.64 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 265.33 358.27 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 182.36 369.37 Tm (IPF) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 118.30 275.07 Tm (IPF) Tj ET 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 29.06 248.52 m 268.45 308.93 l S 0.75 w [ 3.00 5.00] 0 d 29.06 293.66 m 268.45 354.08 l S Q q 307.48 222.24 258.54 154.28 re W n Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 335.89 222.24 m 564.35 222.24 l S 335.89 222.24 m 335.89 219.86 l S 373.97 222.24 m 373.97 219.86 l S 412.04 222.24 m 412.04 219.86 l S 450.12 222.24 m 450.12 219.86 l S 488.19 222.24 m 488.19 219.86 l S 526.27 222.24 m 526.27 219.86 l S 564.35 222.24 m 564.35 219.86 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 4.00 0.00 -0.00 4.00 333.11 213.68 Tm (9.0) Tj ET BT /F2 1 Tf 4.00 0.00 -0.00 4.00 371.19 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764.90 m 256.25 764.90 l S 254.97 768.83 m 256.25 768.83 l S 254.97 772.75 m 256.25 772.75 l S 254.97 776.68 m 256.25 776.68 l S 254.97 780.60 m 256.25 780.60 l S 254.97 784.53 m 256.25 784.53 l S 254.97 788.45 m 256.25 788.45 l S 254.97 792.38 m 256.25 792.38 l S 254.97 796.30 m 256.25 796.30 l S 254.97 800.22 m 256.25 800.22 l S 254.97 804.15 m 256.25 804.15 l S 254.97 808.07 m 256.25 808.07 l S 254.97 812.00 m 256.25 812.00 l S 254.97 815.92 m 256.25 815.92 l S 254.97 819.85 m 256.25 819.85 l S 254.97 823.77 m 256.25 823.77 l S 254.97 702.11 m 254.97 819.85 l S 254.97 702.11 m 257.54 702.11 l S 254.97 721.73 m 257.54 721.73 l S 254.97 741.35 m 257.54 741.35 l S 254.97 760.98 m 257.54 760.98 l S 254.97 780.60 m 257.54 780.60 l S 254.97 800.22 m 257.54 800.22 l S 254.97 819.85 m 257.54 819.85 l S BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 697.55 Tm (-3) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 717.17 Tm (-2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 736.79 Tm (-1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 758.75 Tm (0) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 778.38 Tm (1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 798.00 Tm (2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 817.62 Tm (3) Tj ET 254.97 825.03 m 254.97 696.47 l 412.04 696.47 l S BT /F4 1 Tf 12.00 0.00 -0.00 12.00 254.32 665.11 Tm [(Quantiles of Standard Nor) -25 (mal)] TJ ET BT /F2 1 Tf 0.00 12.00 -12.00 0.00 233.76 817.22 Tm (R) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 235.96 825.88 Tm (1) Tj ET Q q 470.97 696.47 157.08 128.56 re W n Q q 470.97 696.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 475.00 725.34 m 478.57 728.90 l S 475.00 728.90 m 478.57 725.34 l S 492.95 733.53 m 496.51 737.10 l S 492.95 737.10 m 496.51 733.53 l S 502.80 733.77 m 506.37 737.33 l S 502.80 737.33 m 506.37 733.77 l S 510.07 734.72 m 513.64 738.28 l S 510.07 738.28 m 513.64 734.72 l S 516.05 736.53 m 519.61 740.10 l S 516.05 740.10 m 519.61 736.53 l S 521.25 737.45 m 524.81 741.01 l S 521.25 741.01 m 524.81 737.45 l S 525.93 748.64 m 529.50 752.20 l S 525.93 752.20 m 529.50 748.64 l S 530.27 749.67 m 533.84 753.24 l S 530.27 753.24 m 533.84 749.67 l S 534.37 753.03 m 537.93 756.60 l S 534.37 756.60 m 537.93 753.03 l S 538.29 755.37 m 541.86 758.94 l S 538.29 758.94 m 541.86 755.37 l S 542.11 757.74 m 545.67 761.30 l S 542.11 761.30 m 545.67 757.74 l S 545.86 761.83 m 549.42 765.40 l S 545.86 765.40 m 549.42 761.83 l S 549.59 764.27 m 553.15 767.84 l S 549.59 767.84 m 553.15 764.27 l S 553.34 765.14 m 556.90 768.70 l S 553.34 768.70 m 556.90 765.14 l S 557.15 765.70 m 560.72 769.27 l S 557.15 769.27 m 560.72 765.70 l S 561.08 765.74 m 564.64 769.31 l S 561.08 769.31 m 564.64 765.74 l S 565.17 766.88 m 568.74 770.44 l S 565.17 770.44 m 568.74 766.88 l S 569.51 767.03 m 573.08 770.60 l S 569.51 770.60 m 573.08 767.03 l S 574.20 767.24 m 577.76 770.81 l S 574.20 770.81 m 577.76 767.24 l S 579.40 774.40 m 582.96 777.96 l S 579.40 777.96 m 582.96 774.40 l S 585.37 780.24 m 588.93 783.80 l S 585.37 783.80 m 588.93 780.24 l S 592.64 782.30 m 596.21 785.86 l S 592.64 785.86 m 596.21 782.30 l S 602.49 788.47 m 606.06 792.03 l S 602.49 792.03 m 606.06 788.47 l S 620.44 805.67 m 624.01 809.24 l S 620.44 809.24 m 624.01 805.67 l S Q q 432.00 648.00 216.00 216.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 10.00 0.00 -0.00 10.00 515.04 840.93 Tm (NM_000017_at) Tj ET Q q 470.97 696.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 474.92 701.23 m 478.65 701.23 l S 492.87 714.59 m 496.60 714.59 l S 502.72 729.54 m 506.45 729.54 l S 509.99 731.88 m 513.72 731.88 l S 515.97 738.49 m 519.70 738.49 l S 521.16 740.08 m 524.89 740.08 l S 525.85 742.67 m 529.58 742.67 l S 530.19 745.65 m 533.92 745.65 l S 534.28 747.45 m 538.01 747.45 l S 538.21 748.60 m 541.94 748.60 l S 542.02 750.04 m 545.75 750.04 l S 545.77 751.95 m 549.50 751.95 l S 549.50 755.39 m 553.23 755.39 l S 553.26 756.23 m 556.99 756.23 l S 557.07 757.48 m 560.80 757.48 l S 560.99 760.61 m 564.73 760.61 l S 565.09 763.25 m 568.82 763.25 l S 569.43 764.81 m 573.16 764.81 l S 574.12 767.58 m 577.85 767.58 l S 579.31 770.49 m 583.04 770.49 l S 585.29 775.08 m 589.02 775.08 l S 592.56 775.42 m 596.29 775.42 l S 602.41 780.00 m 606.14 780.00 l S 620.36 785.94 m 624.09 785.94 l S 474.92 735.50 m 478.65 735.50 l S 492.87 742.06 m 496.60 742.06 l S 502.72 744.75 m 506.45 744.75 l S 509.99 750.17 m 513.72 750.17 l S 515.97 751.89 m 519.70 751.89 l S 521.16 753.78 m 524.89 753.78 l S 525.85 754.74 m 529.58 754.74 l S 530.19 757.19 m 533.92 757.19 l S 534.28 758.73 m 538.01 758.73 l S 538.21 761.73 m 541.94 761.73 l S 542.02 764.12 m 545.75 764.12 l S 545.77 765.36 m 549.50 765.36 l S 549.50 767.54 m 553.23 767.54 l S 553.26 770.20 m 556.99 770.20 l S 557.07 772.78 m 560.80 772.78 l S 560.99 774.52 m 564.73 774.52 l S 565.09 778.54 m 568.82 778.54 l S 569.43 780.20 m 573.16 780.20 l S 574.12 782.81 m 577.85 782.81 l S 579.31 785.79 m 583.04 785.79 l S 585.29 790.05 m 589.02 790.05 l S 592.56 794.65 m 596.29 794.65 l S 602.41 799.78 m 606.14 799.78 l S 620.36 820.27 m 624.09 820.27 l S Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 474.53 696.47 m 624.48 696.47 l S 474.53 696.47 m 474.53 697.76 l S 478.10 696.47 m 478.10 697.76 l S 481.67 696.47 m 481.67 697.76 l S 485.24 696.47 m 485.24 697.76 l S 488.81 696.47 m 488.81 697.76 l S 492.38 696.47 m 492.38 697.76 l S 495.95 696.47 m 495.95 697.76 l S 499.52 696.47 m 499.52 697.76 l S 503.09 696.47 m 503.09 697.76 l S 506.66 696.47 m 506.66 697.76 l S 510.23 696.47 m 510.23 697.76 l S 513.80 696.47 m 513.80 697.76 l S 517.37 696.47 m 517.37 697.76 l S 520.94 696.47 m 520.94 697.76 l S 524.51 696.47 m 524.51 697.76 l S 528.08 696.47 m 528.08 697.76 l S 531.65 696.47 m 531.65 697.76 l S 535.22 696.47 m 535.22 697.76 l S 538.79 696.47 m 538.79 697.76 l S 542.36 696.47 m 542.36 697.76 l S 545.93 696.47 m 545.93 697.76 l S 549.50 696.47 m 549.50 697.76 l S 553.07 696.47 m 553.07 697.76 l S 556.64 696.47 m 556.64 697.76 l S 560.21 696.47 m 560.21 697.76 l S 563.78 696.47 m 563.78 697.76 l S 567.36 696.47 m 567.36 697.76 l S 570.93 696.47 m 570.93 697.76 l S 574.50 696.47 m 574.50 697.76 l S 578.07 696.47 m 578.07 697.76 l S 581.64 696.47 m 581.64 697.76 l S 585.21 696.47 m 585.21 697.76 l S 588.78 696.47 m 588.78 697.76 l S 592.35 696.47 m 592.35 697.76 l S 595.92 696.47 m 595.92 697.76 l S 599.49 696.47 m 599.49 697.76 l S 603.06 696.47 m 603.06 697.76 l S 606.63 696.47 m 606.63 697.76 l S 610.20 696.47 m 610.20 697.76 l S 613.77 696.47 m 613.77 697.76 l S 617.34 696.47 m 617.34 697.76 l S 620.91 696.47 m 620.91 697.76 l S 624.48 696.47 m 624.48 697.76 l S 478.10 696.47 m 620.91 696.47 l S 478.10 696.47 m 478.10 699.04 l S 495.95 696.47 m 495.95 699.04 l S 513.80 696.47 m 513.80 699.04 l S 531.65 696.47 m 531.65 699.04 l S 549.50 696.47 m 549.50 699.04 l S 567.36 696.47 m 567.36 699.04 l S 585.21 696.47 m 585.21 699.04 l S 603.06 696.47 m 603.06 699.04 l S 620.91 696.47 m 620.91 699.04 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 8.00 0.00 -0.00 8.00 470.20 679.36 Tm (-2.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 505.91 679.36 Tm (-1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 543.94 679.36 Tm (0.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 561.80 679.36 Tm (0.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 579.65 679.36 Tm (1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 597.50 679.36 Tm (1.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 615.35 679.36 Tm (2.0) Tj ET 470.97 698.18 m 470.97 823.77 l S 470.97 698.18 m 472.25 698.18 l S 470.97 702.11 m 472.25 702.11 l S 470.97 706.03 m 472.25 706.03 l S 470.97 709.96 m 472.25 709.96 l S 470.97 713.88 m 472.25 713.88 l S 470.97 717.81 m 472.25 717.81 l S 470.97 721.73 m 472.25 721.73 l S 470.97 725.66 m 472.25 725.66 l S 470.97 729.58 m 472.25 729.58 l S 470.97 733.51 m 472.25 733.51 l S 470.97 737.43 m 472.25 737.43 l S 470.97 741.35 m 472.25 741.35 l S 470.97 745.28 m 472.25 745.28 l S 470.97 749.20 m 472.25 749.20 l S 470.97 753.13 m 472.25 753.13 l S 470.97 757.05 m 472.25 757.05 l S 470.97 760.98 m 472.25 760.98 l S 470.97 764.90 m 472.25 764.90 l S 470.97 768.83 m 472.25 768.83 l S 470.97 772.75 m 472.25 772.75 l S 470.97 776.68 m 472.25 776.68 l S 470.97 780.60 m 472.25 780.60 l S 470.97 784.53 m 472.25 784.53 l S 470.97 788.45 m 472.25 788.45 l S 470.97 792.38 m 472.25 792.38 l S 470.97 796.30 m 472.25 796.30 l S 470.97 800.22 m 472.25 800.22 l S 470.97 804.15 m 472.25 804.15 l S 470.97 808.07 m 472.25 808.07 l S 470.97 812.00 m 472.25 812.00 l S 470.97 815.92 m 472.25 815.92 l S 470.97 819.85 m 472.25 819.85 l S 470.97 823.77 m 472.25 823.77 l S 470.97 702.11 m 470.97 819.85 l S 470.97 702.11 m 473.54 702.11 l S 470.97 721.73 m 473.54 721.73 l S 470.97 741.35 m 473.54 741.35 l S 470.97 760.98 m 473.54 760.98 l S 470.97 780.60 m 473.54 780.60 l S 470.97 800.22 m 473.54 800.22 l S 470.97 819.85 m 473.54 819.85 l S BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 697.55 Tm (-3) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 717.17 Tm (-2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 736.79 Tm (-1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 758.75 Tm (0) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 778.38 Tm (1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 798.00 Tm (2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 817.62 Tm (3) Tj ET 470.97 825.03 m 470.97 696.47 l 628.04 696.47 l S BT /F4 1 Tf 12.00 0.00 -0.00 12.00 470.32 665.11 Tm [(Quantiles of Standard Nor) -25 (mal)] TJ ET BT /F2 1 Tf 0.00 12.00 -12.00 0.00 449.76 817.22 Tm (R) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 451.96 825.88 Tm (1) Tj ET Q q 38.97 480.47 157.08 128.56 re W n Q q 38.97 480.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 43.00 505.96 m 46.57 509.52 l S 43.00 509.52 m 46.57 505.96 l S 60.95 512.55 m 64.51 516.11 l S 60.95 516.11 m 64.51 512.55 l S 70.80 517.89 m 74.37 521.45 l S 70.80 521.45 m 74.37 517.89 l S 78.07 518.26 m 81.64 521.83 l S 78.07 521.83 m 81.64 518.26 l S 84.05 527.80 m 87.61 531.37 l S 84.05 531.37 m 87.61 527.80 l S 89.25 528.72 m 92.81 532.28 l S 89.25 532.28 m 92.81 528.72 l S 93.93 531.45 m 97.50 535.02 l S 93.93 535.02 m 97.50 531.45 l S 98.27 533.29 m 101.84 536.86 l S 98.27 536.86 m 101.84 533.29 l S 102.37 534.08 m 105.93 537.64 l S 102.37 537.64 m 105.93 534.08 l S 106.29 537.62 m 109.86 541.18 l S 106.29 541.18 m 109.86 537.62 l S 110.11 539.69 m 113.67 543.25 l S 110.11 543.25 m 113.67 539.69 l S 113.86 541.30 m 117.42 544.87 l S 113.86 544.87 m 117.42 541.30 l S 117.59 543.36 m 121.15 546.93 l S 117.59 546.93 m 121.15 543.36 l S 121.34 548.07 m 124.90 551.63 l S 121.34 551.63 m 124.90 548.07 l S 125.15 548.12 m 128.72 551.69 l S 125.15 551.69 m 128.72 548.12 l S 129.08 549.61 m 132.64 553.17 l S 129.08 553.17 m 132.64 549.61 l S 133.17 556.27 m 136.74 559.83 l S 133.17 559.83 m 136.74 556.27 l S 137.51 556.31 m 141.08 559.87 l S 137.51 559.87 m 141.08 556.31 l S 142.20 557.43 m 145.76 560.99 l S 142.20 560.99 m 145.76 557.43 l S 147.40 559.10 m 150.96 562.66 l S 147.40 562.66 m 150.96 559.10 l S 153.37 564.11 m 156.93 567.68 l S 153.37 567.68 m 156.93 564.11 l S 160.64 570.87 m 164.21 574.44 l S 160.64 574.44 m 164.21 570.87 l S 170.49 574.00 m 174.06 577.56 l S 170.49 577.56 m 174.06 574.00 l S 188.44 580.83 m 192.01 584.40 l S 188.44 584.40 m 192.01 580.83 l S Q q 0.00 432.00 216.00 216.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 10.00 0.00 -0.00 10.00 83.04 624.93 Tm (NM_000018_at) Tj ET Q q 38.97 480.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 42.92 485.23 m 46.65 485.23 l S 60.87 498.59 m 64.60 498.59 l S 70.72 513.54 m 74.45 513.54 l S 77.99 515.88 m 81.72 515.88 l S 83.97 522.49 m 87.70 522.49 l S 89.16 524.08 m 92.89 524.08 l S 93.85 526.67 m 97.58 526.67 l S 98.19 529.65 m 101.92 529.65 l S 102.28 531.45 m 106.01 531.45 l S 106.21 532.60 m 109.94 532.60 l S 110.02 534.04 m 113.75 534.04 l S 113.77 535.95 m 117.50 535.95 l S 117.50 539.39 m 121.23 539.39 l S 121.26 540.23 m 124.99 540.23 l S 125.07 541.48 m 128.80 541.48 l S 128.99 544.61 m 132.73 544.61 l S 133.09 547.25 m 136.82 547.25 l S 137.43 548.81 m 141.16 548.81 l S 142.12 551.58 m 145.85 551.58 l S 147.31 554.49 m 151.04 554.49 l S 153.29 559.08 m 157.02 559.08 l S 160.56 559.42 m 164.29 559.42 l S 170.41 564.00 m 174.14 564.00 l S 188.36 569.94 m 192.09 569.94 l S 42.92 519.50 m 46.65 519.50 l S 60.87 526.06 m 64.60 526.06 l S 70.72 528.75 m 74.45 528.75 l S 77.99 534.17 m 81.72 534.17 l S 83.97 535.89 m 87.70 535.89 l S 89.16 537.78 m 92.89 537.78 l S 93.85 538.74 m 97.58 538.74 l S 98.19 541.19 m 101.92 541.19 l S 102.28 542.73 m 106.01 542.73 l S 106.21 545.73 m 109.94 545.73 l S 110.02 548.12 m 113.75 548.12 l S 113.77 549.36 m 117.50 549.36 l S 117.50 551.54 m 121.23 551.54 l S 121.26 554.20 m 124.99 554.20 l S 125.07 556.78 m 128.80 556.78 l S 128.99 558.52 m 132.73 558.52 l S 133.09 562.54 m 136.82 562.54 l S 137.43 564.20 m 141.16 564.20 l S 142.12 566.81 m 145.85 566.81 l S 147.31 569.79 m 151.04 569.79 l S 153.29 574.05 m 157.02 574.05 l S 160.56 578.65 m 164.29 578.65 l S 170.41 583.78 m 174.14 583.78 l S 188.36 604.27 m 192.09 604.27 l S Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 42.53 480.47 m 192.48 480.47 l S 42.53 480.47 m 42.53 481.76 l S 46.10 480.47 m 46.10 481.76 l S 49.67 480.47 m 49.67 481.76 l S 53.24 480.47 m 53.24 481.76 l S 56.81 480.47 m 56.81 481.76 l S 60.38 480.47 m 60.38 481.76 l S 63.95 480.47 m 63.95 481.76 l S 67.52 480.47 m 67.52 481.76 l S 71.09 480.47 m 71.09 481.76 l S 74.66 480.47 m 74.66 481.76 l S 78.23 480.47 m 78.23 481.76 l S 81.80 480.47 m 81.80 481.76 l S 85.37 480.47 m 85.37 481.76 l S 88.94 480.47 m 88.94 481.76 l S 92.51 480.47 m 92.51 481.76 l S 96.08 480.47 m 96.08 481.76 l S 99.65 480.47 m 99.65 481.76 l S 103.22 480.47 m 103.22 481.76 l S 106.79 480.47 m 106.79 481.76 l S 110.36 480.47 m 110.36 481.76 l S 113.93 480.47 m 113.93 481.76 l S 117.50 480.47 m 117.50 481.76 l S 121.07 480.47 m 121.07 481.76 l S 124.64 480.47 m 124.64 481.76 l S 128.21 480.47 m 128.21 481.76 l S 131.78 480.47 m 131.78 481.76 l S 135.36 480.47 m 135.36 481.76 l S 138.93 480.47 m 138.93 481.76 l S 142.50 480.47 m 142.50 481.76 l S 146.07 480.47 m 146.07 481.76 l S 149.64 480.47 m 149.64 481.76 l S 153.21 480.47 m 153.21 481.76 l S 156.78 480.47 m 156.78 481.76 l S 160.35 480.47 m 160.35 481.76 l S 163.92 480.47 m 163.92 481.76 l S 167.49 480.47 m 167.49 481.76 l S 171.06 480.47 m 171.06 481.76 l S 174.63 480.47 m 174.63 481.76 l S 178.20 480.47 m 178.20 481.76 l S 181.77 480.47 m 181.77 481.76 l S 185.34 480.47 m 185.34 481.76 l S 188.91 480.47 m 188.91 481.76 l S 192.48 480.47 m 192.48 481.76 l S 46.10 480.47 m 188.91 480.47 l S 46.10 480.47 m 46.10 483.04 l S 63.95 480.47 m 63.95 483.04 l S 81.80 480.47 m 81.80 483.04 l S 99.65 480.47 m 99.65 483.04 l S 117.50 480.47 m 117.50 483.04 l S 135.36 480.47 m 135.36 483.04 l S 153.21 480.47 m 153.21 483.04 l S 171.06 480.47 m 171.06 483.04 l S 188.91 480.47 m 188.91 483.04 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 8.00 0.00 -0.00 8.00 38.20 463.36 Tm (-2.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 73.91 463.36 Tm (-1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 111.94 463.36 Tm (0.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 129.80 463.36 Tm (0.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 147.65 463.36 Tm (1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 165.50 463.36 Tm (1.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 183.35 463.36 Tm (2.0) Tj ET 38.97 482.18 m 38.97 607.77 l S 38.97 482.18 m 40.25 482.18 l S 38.97 486.11 m 40.25 486.11 l S 38.97 490.03 m 40.25 490.03 l S 38.97 493.96 m 40.25 493.96 l S 38.97 497.88 m 40.25 497.88 l S 38.97 501.81 m 40.25 501.81 l S 38.97 505.73 m 40.25 505.73 l S 38.97 509.66 m 40.25 509.66 l S 38.97 513.58 m 40.25 513.58 l S 38.97 517.51 m 40.25 517.51 l S 38.97 521.43 m 40.25 521.43 l S 38.97 525.35 m 40.25 525.35 l S 38.97 529.28 m 40.25 529.28 l S 38.97 533.20 m 40.25 533.20 l S 38.97 537.13 m 40.25 537.13 l S 38.97 541.05 m 40.25 541.05 l S 38.97 544.98 m 40.25 544.98 l S 38.97 548.90 m 40.25 548.90 l S 38.97 552.83 m 40.25 552.83 l S 38.97 556.75 m 40.25 556.75 l S 38.97 560.68 m 40.25 560.68 l S 38.97 564.60 m 40.25 564.60 l S 38.97 568.53 m 40.25 568.53 l S 38.97 572.45 m 40.25 572.45 l S 38.97 576.38 m 40.25 576.38 l S 38.97 580.30 m 40.25 580.30 l S 38.97 584.22 m 40.25 584.22 l S 38.97 588.15 m 40.25 588.15 l S 38.97 592.07 m 40.25 592.07 l S 38.97 596.00 m 40.25 596.00 l S 38.97 599.92 m 40.25 599.92 l S 38.97 603.85 m 40.25 603.85 l S 38.97 607.77 m 40.25 607.77 l S 38.97 486.11 m 38.97 603.85 l S 38.97 486.11 m 41.54 486.11 l S 38.97 505.73 m 41.54 505.73 l S 38.97 525.35 m 41.54 525.35 l S 38.97 544.98 m 41.54 544.98 l S 38.97 564.60 m 41.54 564.60 l S 38.97 584.22 m 41.54 584.22 l S 38.97 603.85 m 41.54 603.85 l S BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 481.55 Tm (-3) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 501.17 Tm (-2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 520.79 Tm (-1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 542.75 Tm (0) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 562.38 Tm (1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 582.00 Tm (2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 601.62 Tm (3) Tj ET 38.97 609.03 m 38.97 480.47 l 196.04 480.47 l S BT /F4 1 Tf 12.00 0.00 -0.00 12.00 38.32 449.11 Tm [(Quantiles of Standard Nor) -25 (mal)] TJ ET BT /F2 1 Tf 0.00 12.00 -12.00 0.00 17.76 601.22 Tm (R) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 19.96 609.88 Tm (1) Tj ET Q q 254.97 480.47 157.08 128.56 re W n Q q 254.97 480.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 259.00 508.97 m 262.57 512.53 l S 259.00 512.53 m 262.57 508.97 l S 276.95 515.94 m 280.51 519.51 l S 276.95 519.51 m 280.51 515.94 l S 286.80 518.99 m 290.37 522.55 l S 286.80 522.55 m 290.37 518.99 l S 294.07 521.16 m 297.64 524.72 l S 294.07 524.72 m 297.64 521.16 l S 300.05 524.65 m 303.61 528.22 l S 300.05 528.22 m 303.61 524.65 l S 305.25 534.65 m 308.81 538.21 l S 305.25 538.21 m 308.81 534.65 l S 309.93 535.13 m 313.50 538.69 l S 309.93 538.69 m 313.50 535.13 l S 314.27 535.81 m 317.84 539.38 l S 314.27 539.38 m 317.84 535.81 l S 318.37 536.45 m 321.93 540.01 l S 318.37 540.01 m 321.93 536.45 l S 322.29 536.92 m 325.86 540.48 l S 322.29 540.48 m 325.86 536.92 l S 326.11 537.07 m 329.67 540.64 l S 326.11 540.64 m 329.67 537.07 l S 329.86 538.33 m 333.42 541.89 l S 329.86 541.89 m 333.42 538.33 l S 333.59 540.56 m 337.15 544.12 l S 333.59 544.12 m 337.15 540.56 l S 337.34 543.49 m 340.90 547.05 l S 337.34 547.05 m 340.90 543.49 l S 341.15 544.32 m 344.72 547.88 l S 341.15 547.88 m 344.72 544.32 l S 345.08 544.46 m 348.64 548.02 l S 345.08 548.02 m 348.64 544.46 l S 349.17 552.10 m 352.74 555.66 l S 349.17 555.66 m 352.74 552.10 l S 353.51 552.16 m 357.08 555.72 l S 353.51 555.72 m 357.08 552.16 l S 358.20 555.34 m 361.76 558.91 l S 358.20 558.91 m 361.76 555.34 l S 363.40 557.60 m 366.96 561.16 l S 363.40 561.16 m 366.96 557.60 l S 369.37 560.05 m 372.93 563.62 l S 369.37 563.62 m 372.93 560.05 l S 376.64 573.57 m 380.21 577.13 l S 376.64 577.13 m 380.21 573.57 l S 386.49 579.73 m 390.06 583.30 l S 386.49 583.30 m 390.06 579.73 l S 404.44 589.26 m 408.01 592.82 l S 404.44 592.82 m 408.01 589.26 l S Q q 216.00 432.00 216.00 216.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 10.00 0.00 -0.00 10.00 299.04 624.93 Tm (NM_000019_at) Tj ET Q q 254.97 480.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 258.92 485.23 m 262.65 485.23 l S 276.87 498.59 m 280.60 498.59 l S 286.72 513.54 m 290.45 513.54 l S 293.99 515.88 m 297.72 515.88 l S 299.97 522.49 m 303.70 522.49 l S 305.16 524.08 m 308.89 524.08 l S 309.85 526.67 m 313.58 526.67 l S 314.19 529.65 m 317.92 529.65 l S 318.28 531.45 m 322.01 531.45 l S 322.21 532.60 m 325.94 532.60 l S 326.02 534.04 m 329.75 534.04 l S 329.77 535.95 m 333.50 535.95 l S 333.50 539.39 m 337.23 539.39 l S 337.26 540.23 m 340.99 540.23 l S 341.07 541.48 m 344.80 541.48 l S 344.99 544.61 m 348.73 544.61 l S 349.09 547.25 m 352.82 547.25 l S 353.43 548.81 m 357.16 548.81 l S 358.12 551.58 m 361.85 551.58 l S 363.31 554.49 m 367.04 554.49 l S 369.29 559.08 m 373.02 559.08 l S 376.56 559.42 m 380.29 559.42 l S 386.41 564.00 m 390.14 564.00 l S 404.36 569.94 m 408.09 569.94 l S 258.92 519.50 m 262.65 519.50 l S 276.87 526.06 m 280.60 526.06 l S 286.72 528.75 m 290.45 528.75 l S 293.99 534.17 m 297.72 534.17 l S 299.97 535.89 m 303.70 535.89 l S 305.16 537.78 m 308.89 537.78 l S 309.85 538.74 m 313.58 538.74 l S 314.19 541.19 m 317.92 541.19 l S 318.28 542.73 m 322.01 542.73 l S 322.21 545.73 m 325.94 545.73 l S 326.02 548.12 m 329.75 548.12 l S 329.77 549.36 m 333.50 549.36 l S 333.50 551.54 m 337.23 551.54 l S 337.26 554.20 m 340.99 554.20 l S 341.07 556.78 m 344.80 556.78 l S 344.99 558.52 m 348.73 558.52 l S 349.09 562.54 m 352.82 562.54 l S 353.43 564.20 m 357.16 564.20 l S 358.12 566.81 m 361.85 566.81 l S 363.31 569.79 m 367.04 569.79 l S 369.29 574.05 m 373.02 574.05 l S 376.56 578.65 m 380.29 578.65 l S 386.41 583.78 m 390.14 583.78 l S 404.36 604.27 m 408.09 604.27 l S Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 258.53 480.47 m 408.48 480.47 l S 258.53 480.47 m 258.53 481.76 l S 262.10 480.47 m 262.10 481.76 l S 265.67 480.47 m 265.67 481.76 l S 269.24 480.47 m 269.24 481.76 l S 272.81 480.47 m 272.81 481.76 l S 276.38 480.47 m 276.38 481.76 l S 279.95 480.47 m 279.95 481.76 l S 283.52 480.47 m 283.52 481.76 l S 287.09 480.47 m 287.09 481.76 l S 290.66 480.47 m 290.66 481.76 l S 294.23 480.47 m 294.23 481.76 l S 297.80 480.47 m 297.80 481.76 l S 301.37 480.47 m 301.37 481.76 l S 304.94 480.47 m 304.94 481.76 l S 308.51 480.47 m 308.51 481.76 l S 312.08 480.47 m 312.08 481.76 l S 315.65 480.47 m 315.65 481.76 l S 319.22 480.47 m 319.22 481.76 l S 322.79 480.47 m 322.79 481.76 l S 326.36 480.47 m 326.36 481.76 l S 329.93 480.47 m 329.93 481.76 l S 333.50 480.47 m 333.50 481.76 l S 337.07 480.47 m 337.07 481.76 l S 340.64 480.47 m 340.64 481.76 l S 344.21 480.47 m 344.21 481.76 l S 347.78 480.47 m 347.78 481.76 l S 351.36 480.47 m 351.36 481.76 l S 354.93 480.47 m 354.93 481.76 l S 358.50 480.47 m 358.50 481.76 l S 362.07 480.47 m 362.07 481.76 l S 365.64 480.47 m 365.64 481.76 l S 369.21 480.47 m 369.21 481.76 l S 372.78 480.47 m 372.78 481.76 l S 376.35 480.47 m 376.35 481.76 l S 379.92 480.47 m 379.92 481.76 l S 383.49 480.47 m 383.49 481.76 l S 387.06 480.47 m 387.06 481.76 l S 390.63 480.47 m 390.63 481.76 l S 394.20 480.47 m 394.20 481.76 l S 397.77 480.47 m 397.77 481.76 l S 401.34 480.47 m 401.34 481.76 l S 404.91 480.47 m 404.91 481.76 l S 408.48 480.47 m 408.48 481.76 l S 262.10 480.47 m 404.91 480.47 l S 262.10 480.47 m 262.10 483.04 l S 279.95 480.47 m 279.95 483.04 l S 297.80 480.47 m 297.80 483.04 l S 315.65 480.47 m 315.65 483.04 l S 333.50 480.47 m 333.50 483.04 l S 351.36 480.47 m 351.36 483.04 l S 369.21 480.47 m 369.21 483.04 l S 387.06 480.47 m 387.06 483.04 l S 404.91 480.47 m 404.91 483.04 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 8.00 0.00 -0.00 8.00 254.20 463.36 Tm (-2.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 289.91 463.36 Tm (-1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 327.94 463.36 Tm (0.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 345.80 463.36 Tm (0.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 363.65 463.36 Tm (1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 381.50 463.36 Tm (1.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 399.35 463.36 Tm (2.0) Tj ET 254.97 482.18 m 254.97 607.77 l S 254.97 482.18 m 256.25 482.18 l S 254.97 486.11 m 256.25 486.11 l S 254.97 490.03 m 256.25 490.03 l S 254.97 493.96 m 256.25 493.96 l S 254.97 497.88 m 256.25 497.88 l S 254.97 501.81 m 256.25 501.81 l S 254.97 505.73 m 256.25 505.73 l S 254.97 509.66 m 256.25 509.66 l S 254.97 513.58 m 256.25 513.58 l S 254.97 517.51 m 256.25 517.51 l S 254.97 521.43 m 256.25 521.43 l S 254.97 525.35 m 256.25 525.35 l S 254.97 529.28 m 256.25 529.28 l S 254.97 533.20 m 256.25 533.20 l S 254.97 537.13 m 256.25 537.13 l S 254.97 541.05 m 256.25 541.05 l S 254.97 544.98 m 256.25 544.98 l S 254.97 548.90 m 256.25 548.90 l S 254.97 552.83 m 256.25 552.83 l S 254.97 556.75 m 256.25 556.75 l S 254.97 560.68 m 256.25 560.68 l S 254.97 564.60 m 256.25 564.60 l S 254.97 568.53 m 256.25 568.53 l S 254.97 572.45 m 256.25 572.45 l S 254.97 576.38 m 256.25 576.38 l S 254.97 580.30 m 256.25 580.30 l S 254.97 584.22 m 256.25 584.22 l S 254.97 588.15 m 256.25 588.15 l S 254.97 592.07 m 256.25 592.07 l S 254.97 596.00 m 256.25 596.00 l S 254.97 599.92 m 256.25 599.92 l S 254.97 603.85 m 256.25 603.85 l S 254.97 607.77 m 256.25 607.77 l S 254.97 486.11 m 254.97 603.85 l S 254.97 486.11 m 257.54 486.11 l S 254.97 505.73 m 257.54 505.73 l S 254.97 525.35 m 257.54 525.35 l S 254.97 544.98 m 257.54 544.98 l S 254.97 564.60 m 257.54 564.60 l S 254.97 584.22 m 257.54 584.22 l S 254.97 603.85 m 257.54 603.85 l S BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 481.55 Tm (-3) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 501.17 Tm (-2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 520.79 Tm (-1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 542.75 Tm (0) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 562.38 Tm (1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 582.00 Tm (2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 601.62 Tm (3) Tj ET 254.97 609.03 m 254.97 480.47 l 412.04 480.47 l S BT /F4 1 Tf 12.00 0.00 -0.00 12.00 254.32 449.11 Tm [(Quantiles of Standard Nor) -25 (mal)] TJ ET BT /F2 1 Tf 0.00 12.00 -12.00 0.00 233.76 601.22 Tm (R) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 235.96 609.88 Tm (1) Tj ET Q q 470.97 480.47 157.08 128.56 re W n Q q 470.97 480.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 475.00 500.01 m 478.57 503.57 l S 475.00 503.57 m 478.57 500.01 l S 492.95 507.04 m 496.51 510.61 l S 492.95 510.61 m 496.51 507.04 l S 502.80 516.23 m 506.37 519.79 l S 502.80 519.79 m 506.37 516.23 l S 510.07 521.80 m 513.64 525.37 l S 510.07 525.37 m 513.64 521.80 l S 516.05 527.45 m 519.61 531.02 l S 516.05 531.02 m 519.61 527.45 l S 521.25 527.89 m 524.81 531.46 l S 521.25 531.46 m 524.81 527.89 l S 525.93 537.91 m 529.50 541.47 l S 525.93 541.47 m 529.50 537.91 l S 530.27 539.14 m 533.84 542.71 l S 530.27 542.71 m 533.84 539.14 l S 534.37 540.12 m 537.93 543.68 l S 534.37 543.68 m 537.93 540.12 l S 538.29 541.66 m 541.86 545.23 l S 538.29 545.23 m 541.86 541.66 l S 542.11 543.73 m 545.67 547.29 l S 542.11 547.29 m 545.67 543.73 l S 545.86 544.14 m 549.42 547.71 l S 545.86 547.71 m 549.42 544.14 l S 549.59 545.42 m 553.15 548.98 l S 549.59 548.98 m 553.15 545.42 l S 553.34 545.65 m 556.90 549.22 l S 553.34 549.22 m 556.90 545.65 l S 557.15 546.31 m 560.72 549.87 l S 557.15 549.87 m 560.72 546.31 l S 561.08 547.13 m 564.64 550.69 l S 561.08 550.69 m 564.64 547.13 l S 565.17 550.26 m 568.74 553.82 l S 565.17 553.82 m 568.74 550.26 l S 569.51 551.51 m 573.08 555.07 l S 569.51 555.07 m 573.08 551.51 l S 574.20 558.25 m 577.76 561.82 l S 574.20 561.82 m 577.76 558.25 l S 579.40 562.45 m 582.96 566.01 l S 579.40 566.01 m 582.96 562.45 l S 585.37 563.46 m 588.93 567.02 l S 585.37 567.02 m 588.93 563.46 l S 592.64 564.77 m 596.21 568.34 l S 592.64 568.34 m 596.21 564.77 l S 602.49 573.92 m 606.06 577.48 l S 602.49 577.48 m 606.06 573.92 l S 620.44 580.45 m 624.01 584.01 l S 620.44 584.01 m 624.01 580.45 l S Q q 432.00 432.00 216.00 216.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 10.00 0.00 -0.00 10.00 515.04 624.93 Tm (NM_000020_at) Tj ET Q q 470.97 480.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 474.92 485.23 m 478.65 485.23 l S 492.87 498.59 m 496.60 498.59 l S 502.72 513.54 m 506.45 513.54 l S 509.99 515.88 m 513.72 515.88 l S 515.97 522.49 m 519.70 522.49 l S 521.16 524.08 m 524.89 524.08 l S 525.85 526.67 m 529.58 526.67 l S 530.19 529.65 m 533.92 529.65 l S 534.28 531.45 m 538.01 531.45 l S 538.21 532.60 m 541.94 532.60 l S 542.02 534.04 m 545.75 534.04 l S 545.77 535.95 m 549.50 535.95 l S 549.50 539.39 m 553.23 539.39 l S 553.26 540.23 m 556.99 540.23 l S 557.07 541.48 m 560.80 541.48 l S 560.99 544.61 m 564.73 544.61 l S 565.09 547.25 m 568.82 547.25 l S 569.43 548.81 m 573.16 548.81 l S 574.12 551.58 m 577.85 551.58 l S 579.31 554.49 m 583.04 554.49 l S 585.29 559.08 m 589.02 559.08 l S 592.56 559.42 m 596.29 559.42 l S 602.41 564.00 m 606.14 564.00 l S 620.36 569.94 m 624.09 569.94 l S 474.92 519.50 m 478.65 519.50 l S 492.87 526.06 m 496.60 526.06 l S 502.72 528.75 m 506.45 528.75 l S 509.99 534.17 m 513.72 534.17 l S 515.97 535.89 m 519.70 535.89 l S 521.16 537.78 m 524.89 537.78 l S 525.85 538.74 m 529.58 538.74 l S 530.19 541.19 m 533.92 541.19 l S 534.28 542.73 m 538.01 542.73 l S 538.21 545.73 m 541.94 545.73 l S 542.02 548.12 m 545.75 548.12 l S 545.77 549.36 m 549.50 549.36 l S 549.50 551.54 m 553.23 551.54 l S 553.26 554.20 m 556.99 554.20 l S 557.07 556.78 m 560.80 556.78 l S 560.99 558.52 m 564.73 558.52 l S 565.09 562.54 m 568.82 562.54 l S 569.43 564.20 m 573.16 564.20 l S 574.12 566.81 m 577.85 566.81 l S 579.31 569.79 m 583.04 569.79 l S 585.29 574.05 m 589.02 574.05 l S 592.56 578.65 m 596.29 578.65 l S 602.41 583.78 m 606.14 583.78 l S 620.36 604.27 m 624.09 604.27 l S Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 474.53 480.47 m 624.48 480.47 l S 474.53 480.47 m 474.53 481.76 l S 478.10 480.47 m 478.10 481.76 l S 481.67 480.47 m 481.67 481.76 l S 485.24 480.47 m 485.24 481.76 l S 488.81 480.47 m 488.81 481.76 l S 492.38 480.47 m 492.38 481.76 l S 495.95 480.47 m 495.95 481.76 l S 499.52 480.47 m 499.52 481.76 l S 503.09 480.47 m 503.09 481.76 l S 506.66 480.47 m 506.66 481.76 l S 510.23 480.47 m 510.23 481.76 l S 513.80 480.47 m 513.80 481.76 l S 517.37 480.47 m 517.37 481.76 l S 520.94 480.47 m 520.94 481.76 l S 524.51 480.47 m 524.51 481.76 l S 528.08 480.47 m 528.08 481.76 l S 531.65 480.47 m 531.65 481.76 l S 535.22 480.47 m 535.22 481.76 l S 538.79 480.47 m 538.79 481.76 l S 542.36 480.47 m 542.36 481.76 l S 545.93 480.47 m 545.93 481.76 l S 549.50 480.47 m 549.50 481.76 l S 553.07 480.47 m 553.07 481.76 l S 556.64 480.47 m 556.64 481.76 l S 560.21 480.47 m 560.21 481.76 l S 563.78 480.47 m 563.78 481.76 l S 567.36 480.47 m 567.36 481.76 l S 570.93 480.47 m 570.93 481.76 l S 574.50 480.47 m 574.50 481.76 l S 578.07 480.47 m 578.07 481.76 l S 581.64 480.47 m 581.64 481.76 l S 585.21 480.47 m 585.21 481.76 l S 588.78 480.47 m 588.78 481.76 l S 592.35 480.47 m 592.35 481.76 l S 595.92 480.47 m 595.92 481.76 l S 599.49 480.47 m 599.49 481.76 l S 603.06 480.47 m 603.06 481.76 l S 606.63 480.47 m 606.63 481.76 l S 610.20 480.47 m 610.20 481.76 l S 613.77 480.47 m 613.77 481.76 l S 617.34 480.47 m 617.34 481.76 l S 620.91 480.47 m 620.91 481.76 l S 624.48 480.47 m 624.48 481.76 l S 478.10 480.47 m 620.91 480.47 l S 478.10 480.47 m 478.10 483.04 l S 495.95 480.47 m 495.95 483.04 l S 513.80 480.47 m 513.80 483.04 l S 531.65 480.47 m 531.65 483.04 l S 549.50 480.47 m 549.50 483.04 l S 567.36 480.47 m 567.36 483.04 l S 585.21 480.47 m 585.21 483.04 l S 603.06 480.47 m 603.06 483.04 l S 620.91 480.47 m 620.91 483.04 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 8.00 0.00 -0.00 8.00 470.20 463.36 Tm (-2.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 505.91 463.36 Tm (-1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 543.94 463.36 Tm (0.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 561.80 463.36 Tm (0.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 579.65 463.36 Tm (1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 597.50 463.36 Tm (1.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 615.35 463.36 Tm (2.0) Tj ET 470.97 482.18 m 470.97 607.77 l S 470.97 482.18 m 472.25 482.18 l S 470.97 486.11 m 472.25 486.11 l S 470.97 490.03 m 472.25 490.03 l S 470.97 493.96 m 472.25 493.96 l S 470.97 497.88 m 472.25 497.88 l S 470.97 501.81 m 472.25 501.81 l S 470.97 505.73 m 472.25 505.73 l S 470.97 509.66 m 472.25 509.66 l S 470.97 513.58 m 472.25 513.58 l S 470.97 517.51 m 472.25 517.51 l S 470.97 521.43 m 472.25 521.43 l S 470.97 525.35 m 472.25 525.35 l S 470.97 529.28 m 472.25 529.28 l S 470.97 533.20 m 472.25 533.20 l S 470.97 537.13 m 472.25 537.13 l S 470.97 541.05 m 472.25 541.05 l S 470.97 544.98 m 472.25 544.98 l S 470.97 548.90 m 472.25 548.90 l S 470.97 552.83 m 472.25 552.83 l S 470.97 556.75 m 472.25 556.75 l S 470.97 560.68 m 472.25 560.68 l S 470.97 564.60 m 472.25 564.60 l S 470.97 568.53 m 472.25 568.53 l S 470.97 572.45 m 472.25 572.45 l S 470.97 576.38 m 472.25 576.38 l S 470.97 580.30 m 472.25 580.30 l S 470.97 584.22 m 472.25 584.22 l S 470.97 588.15 m 472.25 588.15 l S 470.97 592.07 m 472.25 592.07 l S 470.97 596.00 m 472.25 596.00 l S 470.97 599.92 m 472.25 599.92 l S 470.97 603.85 m 472.25 603.85 l S 470.97 607.77 m 472.25 607.77 l S 470.97 486.11 m 470.97 603.85 l S 470.97 486.11 m 473.54 486.11 l S 470.97 505.73 m 473.54 505.73 l S 470.97 525.35 m 473.54 525.35 l S 470.97 544.98 m 473.54 544.98 l S 470.97 564.60 m 473.54 564.60 l S 470.97 584.22 m 473.54 584.22 l S 470.97 603.85 m 473.54 603.85 l S BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 481.55 Tm (-3) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 501.17 Tm (-2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 520.79 Tm (-1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 542.75 Tm (0) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 562.38 Tm (1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 582.00 Tm (2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 601.62 Tm (3) Tj ET 470.97 609.03 m 470.97 480.47 l 628.04 480.47 l S BT /F4 1 Tf 12.00 0.00 -0.00 12.00 470.32 449.11 Tm [(Quantiles of Standard Nor) -25 (mal)] TJ ET BT /F2 1 Tf 0.00 12.00 -12.00 0.00 449.76 601.22 Tm (R) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 451.96 609.88 Tm (1) Tj ET Q q 38.97 264.47 157.08 128.56 re W n Q q 38.97 264.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 43.00 293.59 m 46.57 297.16 l S 43.00 297.16 m 46.57 293.59 l S 60.95 294.67 m 64.51 298.24 l S 60.95 298.24 m 64.51 294.67 l S 70.80 297.92 m 74.37 301.49 l S 70.80 301.49 m 74.37 297.92 l S 78.07 302.60 m 81.64 306.17 l S 78.07 306.17 m 81.64 302.60 l S 84.05 310.69 m 87.61 314.25 l S 84.05 314.25 m 87.61 310.69 l S 89.25 311.46 m 92.81 315.02 l S 89.25 315.02 m 92.81 311.46 l S 93.93 311.74 m 97.50 315.30 l S 93.93 315.30 m 97.50 311.74 l S 98.27 314.93 m 101.84 318.49 l S 98.27 318.49 m 101.84 314.93 l S 102.37 315.95 m 105.93 319.51 l S 102.37 319.51 m 105.93 315.95 l S 106.29 318.29 m 109.86 321.85 l S 106.29 321.85 m 109.86 318.29 l S 110.11 329.18 m 113.67 332.74 l S 110.11 332.74 m 113.67 329.18 l S 113.86 329.59 m 117.42 333.15 l S 113.86 333.15 m 117.42 329.59 l S 117.59 331.20 m 121.15 334.76 l S 117.59 334.76 m 121.15 331.20 l S 121.34 331.71 m 124.90 335.28 l S 121.34 335.28 m 124.90 331.71 l S 125.15 336.84 m 128.72 340.40 l S 125.15 340.40 m 128.72 336.84 l S 129.08 337.35 m 132.64 340.91 l S 129.08 340.91 m 132.64 337.35 l S 133.17 337.53 m 136.74 341.09 l S 133.17 341.09 m 136.74 337.53 l S 137.51 342.03 m 141.08 345.60 l S 137.51 345.60 m 141.08 342.03 l S 142.20 343.24 m 145.76 346.80 l S 142.20 346.80 m 145.76 343.24 l S 147.40 346.86 m 150.96 350.43 l S 147.40 350.43 m 150.96 346.86 l S 153.37 350.74 m 156.93 354.30 l S 153.37 354.30 m 156.93 350.74 l S 160.64 351.36 m 164.21 354.92 l S 160.64 354.92 m 164.21 351.36 l S 170.49 354.49 m 174.06 358.05 l S 170.49 358.05 m 174.06 354.49 l S 188.44 358.76 m 192.01 362.33 l S 188.44 362.33 m 192.01 358.76 l S Q q 0.00 216.00 216.00 216.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 10.00 0.00 -0.00 10.00 83.04 408.93 Tm (NM_000021_at) Tj ET Q q 38.97 264.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 42.92 269.23 m 46.65 269.23 l S 60.87 282.59 m 64.60 282.59 l S 70.72 297.54 m 74.45 297.54 l S 77.99 299.88 m 81.72 299.88 l S 83.97 306.49 m 87.70 306.49 l S 89.16 308.08 m 92.89 308.08 l S 93.85 310.67 m 97.58 310.67 l S 98.19 313.65 m 101.92 313.65 l S 102.28 315.45 m 106.01 315.45 l S 106.21 316.60 m 109.94 316.60 l S 110.02 318.04 m 113.75 318.04 l S 113.77 319.95 m 117.50 319.95 l S 117.50 323.39 m 121.23 323.39 l S 121.26 324.23 m 124.99 324.23 l S 125.07 325.48 m 128.80 325.48 l S 128.99 328.61 m 132.73 328.61 l S 133.09 331.25 m 136.82 331.25 l S 137.43 332.81 m 141.16 332.81 l S 142.12 335.58 m 145.85 335.58 l S 147.31 338.49 m 151.04 338.49 l S 153.29 343.08 m 157.02 343.08 l S 160.56 343.42 m 164.29 343.42 l S 170.41 348.00 m 174.14 348.00 l S 188.36 353.94 m 192.09 353.94 l S 42.92 303.50 m 46.65 303.50 l S 60.87 310.06 m 64.60 310.06 l S 70.72 312.75 m 74.45 312.75 l S 77.99 318.17 m 81.72 318.17 l S 83.97 319.89 m 87.70 319.89 l S 89.16 321.78 m 92.89 321.78 l S 93.85 322.74 m 97.58 322.74 l S 98.19 325.19 m 101.92 325.19 l S 102.28 326.73 m 106.01 326.73 l S 106.21 329.73 m 109.94 329.73 l S 110.02 332.12 m 113.75 332.12 l S 113.77 333.36 m 117.50 333.36 l S 117.50 335.54 m 121.23 335.54 l S 121.26 338.20 m 124.99 338.20 l S 125.07 340.78 m 128.80 340.78 l S 128.99 342.52 m 132.73 342.52 l S 133.09 346.54 m 136.82 346.54 l S 137.43 348.20 m 141.16 348.20 l S 142.12 350.81 m 145.85 350.81 l S 147.31 353.79 m 151.04 353.79 l S 153.29 358.05 m 157.02 358.05 l S 160.56 362.65 m 164.29 362.65 l S 170.41 367.78 m 174.14 367.78 l S 188.36 388.27 m 192.09 388.27 l S Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 42.53 264.47 m 192.48 264.47 l S 42.53 264.47 m 42.53 265.76 l S 46.10 264.47 m 46.10 265.76 l S 49.67 264.47 m 49.67 265.76 l S 53.24 264.47 m 53.24 265.76 l S 56.81 264.47 m 56.81 265.76 l S 60.38 264.47 m 60.38 265.76 l S 63.95 264.47 m 63.95 265.76 l S 67.52 264.47 m 67.52 265.76 l S 71.09 264.47 m 71.09 265.76 l S 74.66 264.47 m 74.66 265.76 l S 78.23 264.47 m 78.23 265.76 l S 81.80 264.47 m 81.80 265.76 l S 85.37 264.47 m 85.37 265.76 l S 88.94 264.47 m 88.94 265.76 l S 92.51 264.47 m 92.51 265.76 l S 96.08 264.47 m 96.08 265.76 l S 99.65 264.47 m 99.65 265.76 l S 103.22 264.47 m 103.22 265.76 l S 106.79 264.47 m 106.79 265.76 l S 110.36 264.47 m 110.36 265.76 l S 113.93 264.47 m 113.93 265.76 l S 117.50 264.47 m 117.50 265.76 l S 121.07 264.47 m 121.07 265.76 l S 124.64 264.47 m 124.64 265.76 l S 128.21 264.47 m 128.21 265.76 l S 131.78 264.47 m 131.78 265.76 l S 135.36 264.47 m 135.36 265.76 l S 138.93 264.47 m 138.93 265.76 l S 142.50 264.47 m 142.50 265.76 l S 146.07 264.47 m 146.07 265.76 l S 149.64 264.47 m 149.64 265.76 l S 153.21 264.47 m 153.21 265.76 l S 156.78 264.47 m 156.78 265.76 l S 160.35 264.47 m 160.35 265.76 l S 163.92 264.47 m 163.92 265.76 l S 167.49 264.47 m 167.49 265.76 l S 171.06 264.47 m 171.06 265.76 l S 174.63 264.47 m 174.63 265.76 l S 178.20 264.47 m 178.20 265.76 l S 181.77 264.47 m 181.77 265.76 l S 185.34 264.47 m 185.34 265.76 l S 188.91 264.47 m 188.91 265.76 l S 192.48 264.47 m 192.48 265.76 l S 46.10 264.47 m 188.91 264.47 l S 46.10 264.47 m 46.10 267.04 l S 63.95 264.47 m 63.95 267.04 l S 81.80 264.47 m 81.80 267.04 l S 99.65 264.47 m 99.65 267.04 l S 117.50 264.47 m 117.50 267.04 l S 135.36 264.47 m 135.36 267.04 l S 153.21 264.47 m 153.21 267.04 l S 171.06 264.47 m 171.06 267.04 l S 188.91 264.47 m 188.91 267.04 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 8.00 0.00 -0.00 8.00 38.20 247.36 Tm (-2.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 73.91 247.36 Tm (-1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 111.94 247.36 Tm (0.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 129.80 247.36 Tm (0.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 147.65 247.36 Tm (1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 165.50 247.36 Tm (1.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 183.35 247.36 Tm (2.0) Tj ET 38.97 266.18 m 38.97 391.77 l S 38.97 266.18 m 40.25 266.18 l S 38.97 270.11 m 40.25 270.11 l S 38.97 274.03 m 40.25 274.03 l S 38.97 277.96 m 40.25 277.96 l S 38.97 281.88 m 40.25 281.88 l S 38.97 285.81 m 40.25 285.81 l S 38.97 289.73 m 40.25 289.73 l S 38.97 293.66 m 40.25 293.66 l S 38.97 297.58 m 40.25 297.58 l S 38.97 301.51 m 40.25 301.51 l S 38.97 305.43 m 40.25 305.43 l S 38.97 309.35 m 40.25 309.35 l S 38.97 313.28 m 40.25 313.28 l S 38.97 317.20 m 40.25 317.20 l S 38.97 321.13 m 40.25 321.13 l S 38.97 325.05 m 40.25 325.05 l S 38.97 328.98 m 40.25 328.98 l S 38.97 332.90 m 40.25 332.90 l S 38.97 336.83 m 40.25 336.83 l S 38.97 340.75 m 40.25 340.75 l S 38.97 344.68 m 40.25 344.68 l S 38.97 348.60 m 40.25 348.60 l S 38.97 352.53 m 40.25 352.53 l S 38.97 356.45 m 40.25 356.45 l S 38.97 360.38 m 40.25 360.38 l S 38.97 364.30 m 40.25 364.30 l S 38.97 368.22 m 40.25 368.22 l S 38.97 372.15 m 40.25 372.15 l S 38.97 376.07 m 40.25 376.07 l S 38.97 380.00 m 40.25 380.00 l S 38.97 383.92 m 40.25 383.92 l S 38.97 387.85 m 40.25 387.85 l S 38.97 391.77 m 40.25 391.77 l S 38.97 270.11 m 38.97 387.85 l S 38.97 270.11 m 41.54 270.11 l S 38.97 289.73 m 41.54 289.73 l S 38.97 309.35 m 41.54 309.35 l S 38.97 328.98 m 41.54 328.98 l S 38.97 348.60 m 41.54 348.60 l S 38.97 368.22 m 41.54 368.22 l S 38.97 387.85 m 41.54 387.85 l S BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 265.55 Tm (-3) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 285.17 Tm (-2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 304.79 Tm (-1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 326.75 Tm (0) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 346.38 Tm (1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 366.00 Tm (2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 385.62 Tm (3) Tj ET 38.97 393.03 m 38.97 264.47 l 196.04 264.47 l S BT /F4 1 Tf 12.00 0.00 -0.00 12.00 38.32 233.11 Tm [(Quantiles of Standard Nor) -25 (mal)] TJ ET BT /F2 1 Tf 0.00 12.00 -12.00 0.00 17.76 385.22 Tm (R) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 19.96 393.88 Tm (1) Tj ET Q q 254.97 264.47 157.08 128.56 re W n Q q 254.97 264.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 259.00 289.07 m 262.57 292.63 l S 259.00 292.63 m 262.57 289.07 l S 276.95 298.80 m 280.51 302.36 l S 276.95 302.36 m 280.51 298.80 l S 286.80 300.65 m 290.37 304.21 l S 286.80 304.21 m 290.37 300.65 l S 294.07 310.37 m 297.64 313.93 l S 294.07 313.93 m 297.64 310.37 l S 300.05 314.55 m 303.61 318.12 l S 300.05 318.12 m 303.61 314.55 l S 305.25 315.16 m 308.81 318.72 l S 305.25 318.72 m 308.81 315.16 l S 309.93 315.52 m 313.50 319.08 l S 309.93 319.08 m 313.50 315.52 l S 314.27 316.97 m 317.84 320.53 l S 314.27 320.53 m 317.84 316.97 l S 318.37 319.23 m 321.93 322.80 l S 318.37 322.80 m 321.93 319.23 l S 322.29 320.81 m 325.86 324.37 l S 322.29 324.37 m 325.86 320.81 l S 326.11 322.94 m 329.67 326.50 l S 326.11 326.50 m 329.67 322.94 l S 329.86 324.28 m 333.42 327.85 l S 329.86 327.85 m 333.42 324.28 l S 333.59 326.71 m 337.15 330.27 l S 333.59 330.27 m 337.15 326.71 l S 337.34 329.39 m 340.90 332.95 l S 337.34 332.95 m 340.90 329.39 l S 341.15 331.15 m 344.72 334.71 l S 341.15 334.71 m 344.72 331.15 l S 345.08 333.04 m 348.64 336.61 l S 345.08 336.61 m 348.64 333.04 l S 349.17 333.11 m 352.74 336.67 l S 349.17 336.67 m 352.74 333.11 l S 353.51 340.19 m 357.08 343.75 l S 353.51 343.75 m 357.08 340.19 l S 358.20 340.29 m 361.76 343.86 l S 358.20 343.86 m 361.76 340.29 l S 363.40 342.74 m 366.96 346.30 l S 363.40 346.30 m 366.96 342.74 l S 369.37 343.05 m 372.93 346.61 l S 369.37 346.61 m 372.93 343.05 l S 376.64 345.25 m 380.21 348.81 l S 376.64 348.81 m 380.21 345.25 l S 386.49 363.96 m 390.06 367.53 l S 386.49 367.53 m 390.06 363.96 l S 404.44 375.48 m 408.01 379.04 l S 404.44 379.04 m 408.01 375.48 l S Q q 216.00 216.00 216.00 216.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 10.00 0.00 -0.00 10.00 299.04 408.93 Tm (NM_000022_at) Tj ET Q q 254.97 264.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 258.92 269.23 m 262.65 269.23 l S 276.87 282.59 m 280.60 282.59 l S 286.72 297.54 m 290.45 297.54 l S 293.99 299.88 m 297.72 299.88 l S 299.97 306.49 m 303.70 306.49 l S 305.16 308.08 m 308.89 308.08 l S 309.85 310.67 m 313.58 310.67 l S 314.19 313.65 m 317.92 313.65 l S 318.28 315.45 m 322.01 315.45 l S 322.21 316.60 m 325.94 316.60 l S 326.02 318.04 m 329.75 318.04 l S 329.77 319.95 m 333.50 319.95 l S 333.50 323.39 m 337.23 323.39 l S 337.26 324.23 m 340.99 324.23 l S 341.07 325.48 m 344.80 325.48 l S 344.99 328.61 m 348.73 328.61 l S 349.09 331.25 m 352.82 331.25 l S 353.43 332.81 m 357.16 332.81 l S 358.12 335.58 m 361.85 335.58 l S 363.31 338.49 m 367.04 338.49 l S 369.29 343.08 m 373.02 343.08 l S 376.56 343.42 m 380.29 343.42 l S 386.41 348.00 m 390.14 348.00 l S 404.36 353.94 m 408.09 353.94 l S 258.92 303.50 m 262.65 303.50 l S 276.87 310.06 m 280.60 310.06 l S 286.72 312.75 m 290.45 312.75 l S 293.99 318.17 m 297.72 318.17 l S 299.97 319.89 m 303.70 319.89 l S 305.16 321.78 m 308.89 321.78 l S 309.85 322.74 m 313.58 322.74 l S 314.19 325.19 m 317.92 325.19 l S 318.28 326.73 m 322.01 326.73 l S 322.21 329.73 m 325.94 329.73 l S 326.02 332.12 m 329.75 332.12 l S 329.77 333.36 m 333.50 333.36 l S 333.50 335.54 m 337.23 335.54 l S 337.26 338.20 m 340.99 338.20 l S 341.07 340.78 m 344.80 340.78 l S 344.99 342.52 m 348.73 342.52 l S 349.09 346.54 m 352.82 346.54 l S 353.43 348.20 m 357.16 348.20 l S 358.12 350.81 m 361.85 350.81 l S 363.31 353.79 m 367.04 353.79 l S 369.29 358.05 m 373.02 358.05 l S 376.56 362.65 m 380.29 362.65 l S 386.41 367.78 m 390.14 367.78 l S 404.36 388.27 m 408.09 388.27 l S Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 258.53 264.47 m 408.48 264.47 l S 258.53 264.47 m 258.53 265.76 l S 262.10 264.47 m 262.10 265.76 l S 265.67 264.47 m 265.67 265.76 l S 269.24 264.47 m 269.24 265.76 l S 272.81 264.47 m 272.81 265.76 l S 276.38 264.47 m 276.38 265.76 l S 279.95 264.47 m 279.95 265.76 l S 283.52 264.47 m 283.52 265.76 l S 287.09 264.47 m 287.09 265.76 l S 290.66 264.47 m 290.66 265.76 l S 294.23 264.47 m 294.23 265.76 l S 297.80 264.47 m 297.80 265.76 l S 301.37 264.47 m 301.37 265.76 l S 304.94 264.47 m 304.94 265.76 l S 308.51 264.47 m 308.51 265.76 l S 312.08 264.47 m 312.08 265.76 l S 315.65 264.47 m 315.65 265.76 l S 319.22 264.47 m 319.22 265.76 l S 322.79 264.47 m 322.79 265.76 l S 326.36 264.47 m 326.36 265.76 l S 329.93 264.47 m 329.93 265.76 l S 333.50 264.47 m 333.50 265.76 l S 337.07 264.47 m 337.07 265.76 l S 340.64 264.47 m 340.64 265.76 l S 344.21 264.47 m 344.21 265.76 l S 347.78 264.47 m 347.78 265.76 l S 351.36 264.47 m 351.36 265.76 l S 354.93 264.47 m 354.93 265.76 l S 358.50 264.47 m 358.50 265.76 l S 362.07 264.47 m 362.07 265.76 l S 365.64 264.47 m 365.64 265.76 l S 369.21 264.47 m 369.21 265.76 l S 372.78 264.47 m 372.78 265.76 l S 376.35 264.47 m 376.35 265.76 l S 379.92 264.47 m 379.92 265.76 l S 383.49 264.47 m 383.49 265.76 l S 387.06 264.47 m 387.06 265.76 l S 390.63 264.47 m 390.63 265.76 l S 394.20 264.47 m 394.20 265.76 l S 397.77 264.47 m 397.77 265.76 l S 401.34 264.47 m 401.34 265.76 l S 404.91 264.47 m 404.91 265.76 l S 408.48 264.47 m 408.48 265.76 l S 262.10 264.47 m 404.91 264.47 l S 262.10 264.47 m 262.10 267.04 l S 279.95 264.47 m 279.95 267.04 l S 297.80 264.47 m 297.80 267.04 l S 315.65 264.47 m 315.65 267.04 l S 333.50 264.47 m 333.50 267.04 l S 351.36 264.47 m 351.36 267.04 l S 369.21 264.47 m 369.21 267.04 l S 387.06 264.47 m 387.06 267.04 l S 404.91 264.47 m 404.91 267.04 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 8.00 0.00 -0.00 8.00 254.20 247.36 Tm (-2.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 289.91 247.36 Tm (-1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 327.94 247.36 Tm (0.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 345.80 247.36 Tm (0.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 363.65 247.36 Tm (1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 381.50 247.36 Tm (1.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 399.35 247.36 Tm (2.0) Tj ET 254.97 266.18 m 254.97 391.77 l S 254.97 266.18 m 256.25 266.18 l S 254.97 270.11 m 256.25 270.11 l S 254.97 274.03 m 256.25 274.03 l S 254.97 277.96 m 256.25 277.96 l S 254.97 281.88 m 256.25 281.88 l S 254.97 285.81 m 256.25 285.81 l S 254.97 289.73 m 256.25 289.73 l S 254.97 293.66 m 256.25 293.66 l S 254.97 297.58 m 256.25 297.58 l S 254.97 301.51 m 256.25 301.51 l S 254.97 305.43 m 256.25 305.43 l S 254.97 309.35 m 256.25 309.35 l S 254.97 313.28 m 256.25 313.28 l S 254.97 317.20 m 256.25 317.20 l S 254.97 321.13 m 256.25 321.13 l S 254.97 325.05 m 256.25 325.05 l S 254.97 328.98 m 256.25 328.98 l S 254.97 332.90 m 256.25 332.90 l S 254.97 336.83 m 256.25 336.83 l S 254.97 340.75 m 256.25 340.75 l S 254.97 344.68 m 256.25 344.68 l S 254.97 348.60 m 256.25 348.60 l S 254.97 352.53 m 256.25 352.53 l S 254.97 356.45 m 256.25 356.45 l S 254.97 360.38 m 256.25 360.38 l S 254.97 364.30 m 256.25 364.30 l S 254.97 368.22 m 256.25 368.22 l S 254.97 372.15 m 256.25 372.15 l S 254.97 376.07 m 256.25 376.07 l S 254.97 380.00 m 256.25 380.00 l S 254.97 383.92 m 256.25 383.92 l S 254.97 387.85 m 256.25 387.85 l S 254.97 391.77 m 256.25 391.77 l S 254.97 270.11 m 254.97 387.85 l S 254.97 270.11 m 257.54 270.11 l S 254.97 289.73 m 257.54 289.73 l S 254.97 309.35 m 257.54 309.35 l S 254.97 328.98 m 257.54 328.98 l S 254.97 348.60 m 257.54 348.60 l S 254.97 368.22 m 257.54 368.22 l S 254.97 387.85 m 257.54 387.85 l S BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 265.55 Tm (-3) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 285.17 Tm (-2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 304.79 Tm (-1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 326.75 Tm (0) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 346.38 Tm (1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 366.00 Tm (2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 243.56 385.62 Tm (3) Tj ET 254.97 393.03 m 254.97 264.47 l 412.04 264.47 l S BT /F4 1 Tf 12.00 0.00 -0.00 12.00 254.32 233.11 Tm [(Quantiles of Standard Nor) -25 (mal)] TJ ET BT /F2 1 Tf 0.00 12.00 -12.00 0.00 233.76 385.22 Tm (R) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 235.96 393.88 Tm (1) Tj ET Q q 470.97 264.47 157.08 128.56 re W n Q q 470.97 264.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 475.00 285.56 m 478.57 289.13 l S 475.00 289.13 m 478.57 285.56 l S 492.95 296.19 m 496.51 299.76 l S 492.95 299.76 m 496.51 296.19 l S 502.80 300.86 m 506.37 304.42 l S 502.80 304.42 m 506.37 300.86 l S 510.07 304.94 m 513.64 308.51 l S 510.07 308.51 m 513.64 304.94 l S 516.05 309.92 m 519.61 313.48 l S 516.05 313.48 m 519.61 309.92 l S 521.25 315.56 m 524.81 319.13 l S 521.25 319.13 m 524.81 315.56 l S 525.93 316.96 m 529.50 320.53 l S 525.93 320.53 m 529.50 316.96 l S 530.27 318.09 m 533.84 321.66 l S 530.27 321.66 m 533.84 318.09 l S 534.37 318.76 m 537.93 322.32 l S 534.37 322.32 m 537.93 318.76 l S 538.29 325.36 m 541.86 328.92 l S 538.29 328.92 m 541.86 325.36 l S 542.11 326.31 m 545.67 329.87 l S 542.11 329.87 m 545.67 326.31 l S 545.86 326.96 m 549.42 330.52 l S 545.86 330.52 m 549.42 326.96 l S 549.59 329.58 m 553.15 333.14 l S 549.59 333.14 m 553.15 329.58 l S 553.34 330.93 m 556.90 334.49 l S 553.34 334.49 m 556.90 330.93 l S 557.15 331.61 m 560.72 335.17 l S 557.15 335.17 m 560.72 331.61 l S 561.08 333.74 m 564.64 337.31 l S 561.08 337.31 m 564.64 333.74 l S 565.17 337.42 m 568.74 340.99 l S 565.17 340.99 m 568.74 337.42 l S 569.51 339.97 m 573.08 343.54 l S 569.51 343.54 m 573.08 339.97 l S 574.20 340.29 m 577.76 343.86 l S 574.20 343.86 m 577.76 340.29 l S 579.40 344.62 m 582.96 348.18 l S 579.40 348.18 m 582.96 344.62 l S 585.37 344.72 m 588.93 348.29 l S 585.37 348.29 m 588.93 344.72 l S 592.64 344.90 m 596.21 348.46 l S 592.64 348.46 m 596.21 344.90 l S 602.49 362.04 m 606.06 365.61 l S 602.49 365.61 m 606.06 362.04 l S 620.44 367.40 m 624.01 370.97 l S 620.44 370.97 m 624.01 367.40 l S Q q 432.00 216.00 216.00 216.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 10.00 0.00 -0.00 10.00 515.04 408.93 Tm (NM_000023_at) Tj ET Q q 470.97 264.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 474.92 269.23 m 478.65 269.23 l S 492.87 282.59 m 496.60 282.59 l S 502.72 297.54 m 506.45 297.54 l S 509.99 299.88 m 513.72 299.88 l S 515.97 306.49 m 519.70 306.49 l S 521.16 308.08 m 524.89 308.08 l S 525.85 310.67 m 529.58 310.67 l S 530.19 313.65 m 533.92 313.65 l S 534.28 315.45 m 538.01 315.45 l S 538.21 316.60 m 541.94 316.60 l S 542.02 318.04 m 545.75 318.04 l S 545.77 319.95 m 549.50 319.95 l S 549.50 323.39 m 553.23 323.39 l S 553.26 324.23 m 556.99 324.23 l S 557.07 325.48 m 560.80 325.48 l S 560.99 328.61 m 564.73 328.61 l S 565.09 331.25 m 568.82 331.25 l S 569.43 332.81 m 573.16 332.81 l S 574.12 335.58 m 577.85 335.58 l S 579.31 338.49 m 583.04 338.49 l S 585.29 343.08 m 589.02 343.08 l S 592.56 343.42 m 596.29 343.42 l S 602.41 348.00 m 606.14 348.00 l S 620.36 353.94 m 624.09 353.94 l S 474.92 303.50 m 478.65 303.50 l S 492.87 310.06 m 496.60 310.06 l S 502.72 312.75 m 506.45 312.75 l S 509.99 318.17 m 513.72 318.17 l S 515.97 319.89 m 519.70 319.89 l S 521.16 321.78 m 524.89 321.78 l S 525.85 322.74 m 529.58 322.74 l S 530.19 325.19 m 533.92 325.19 l S 534.28 326.73 m 538.01 326.73 l S 538.21 329.73 m 541.94 329.73 l S 542.02 332.12 m 545.75 332.12 l S 545.77 333.36 m 549.50 333.36 l S 549.50 335.54 m 553.23 335.54 l S 553.26 338.20 m 556.99 338.20 l S 557.07 340.78 m 560.80 340.78 l S 560.99 342.52 m 564.73 342.52 l S 565.09 346.54 m 568.82 346.54 l S 569.43 348.20 m 573.16 348.20 l S 574.12 350.81 m 577.85 350.81 l S 579.31 353.79 m 583.04 353.79 l S 585.29 358.05 m 589.02 358.05 l S 592.56 362.65 m 596.29 362.65 l S 602.41 367.78 m 606.14 367.78 l S 620.36 388.27 m 624.09 388.27 l S Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 474.53 264.47 m 624.48 264.47 l S 474.53 264.47 m 474.53 265.76 l S 478.10 264.47 m 478.10 265.76 l S 481.67 264.47 m 481.67 265.76 l S 485.24 264.47 m 485.24 265.76 l S 488.81 264.47 m 488.81 265.76 l S 492.38 264.47 m 492.38 265.76 l S 495.95 264.47 m 495.95 265.76 l S 499.52 264.47 m 499.52 265.76 l S 503.09 264.47 m 503.09 265.76 l S 506.66 264.47 m 506.66 265.76 l S 510.23 264.47 m 510.23 265.76 l S 513.80 264.47 m 513.80 265.76 l S 517.37 264.47 m 517.37 265.76 l S 520.94 264.47 m 520.94 265.76 l S 524.51 264.47 m 524.51 265.76 l S 528.08 264.47 m 528.08 265.76 l S 531.65 264.47 m 531.65 265.76 l S 535.22 264.47 m 535.22 265.76 l S 538.79 264.47 m 538.79 265.76 l S 542.36 264.47 m 542.36 265.76 l S 545.93 264.47 m 545.93 265.76 l S 549.50 264.47 m 549.50 265.76 l S 553.07 264.47 m 553.07 265.76 l S 556.64 264.47 m 556.64 265.76 l S 560.21 264.47 m 560.21 265.76 l S 563.78 264.47 m 563.78 265.76 l S 567.36 264.47 m 567.36 265.76 l S 570.93 264.47 m 570.93 265.76 l S 574.50 264.47 m 574.50 265.76 l S 578.07 264.47 m 578.07 265.76 l S 581.64 264.47 m 581.64 265.76 l S 585.21 264.47 m 585.21 265.76 l S 588.78 264.47 m 588.78 265.76 l S 592.35 264.47 m 592.35 265.76 l S 595.92 264.47 m 595.92 265.76 l S 599.49 264.47 m 599.49 265.76 l S 603.06 264.47 m 603.06 265.76 l S 606.63 264.47 m 606.63 265.76 l S 610.20 264.47 m 610.20 265.76 l S 613.77 264.47 m 613.77 265.76 l S 617.34 264.47 m 617.34 265.76 l S 620.91 264.47 m 620.91 265.76 l S 624.48 264.47 m 624.48 265.76 l S 478.10 264.47 m 620.91 264.47 l S 478.10 264.47 m 478.10 267.04 l S 495.95 264.47 m 495.95 267.04 l S 513.80 264.47 m 513.80 267.04 l S 531.65 264.47 m 531.65 267.04 l S 549.50 264.47 m 549.50 267.04 l S 567.36 264.47 m 567.36 267.04 l S 585.21 264.47 m 585.21 267.04 l S 603.06 264.47 m 603.06 267.04 l S 620.91 264.47 m 620.91 267.04 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 8.00 0.00 -0.00 8.00 470.20 247.36 Tm (-2.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 505.91 247.36 Tm (-1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 543.94 247.36 Tm (0.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 561.80 247.36 Tm (0.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 579.65 247.36 Tm (1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 597.50 247.36 Tm (1.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 615.35 247.36 Tm (2.0) Tj ET 470.97 266.18 m 470.97 391.77 l S 470.97 266.18 m 472.25 266.18 l S 470.97 270.11 m 472.25 270.11 l S 470.97 274.03 m 472.25 274.03 l S 470.97 277.96 m 472.25 277.96 l S 470.97 281.88 m 472.25 281.88 l S 470.97 285.81 m 472.25 285.81 l S 470.97 289.73 m 472.25 289.73 l S 470.97 293.66 m 472.25 293.66 l S 470.97 297.58 m 472.25 297.58 l S 470.97 301.51 m 472.25 301.51 l S 470.97 305.43 m 472.25 305.43 l S 470.97 309.35 m 472.25 309.35 l S 470.97 313.28 m 472.25 313.28 l S 470.97 317.20 m 472.25 317.20 l S 470.97 321.13 m 472.25 321.13 l S 470.97 325.05 m 472.25 325.05 l S 470.97 328.98 m 472.25 328.98 l S 470.97 332.90 m 472.25 332.90 l S 470.97 336.83 m 472.25 336.83 l S 470.97 340.75 m 472.25 340.75 l S 470.97 344.68 m 472.25 344.68 l S 470.97 348.60 m 472.25 348.60 l S 470.97 352.53 m 472.25 352.53 l S 470.97 356.45 m 472.25 356.45 l S 470.97 360.38 m 472.25 360.38 l S 470.97 364.30 m 472.25 364.30 l S 470.97 368.22 m 472.25 368.22 l S 470.97 372.15 m 472.25 372.15 l S 470.97 376.07 m 472.25 376.07 l S 470.97 380.00 m 472.25 380.00 l S 470.97 383.92 m 472.25 383.92 l S 470.97 387.85 m 472.25 387.85 l S 470.97 391.77 m 472.25 391.77 l S 470.97 270.11 m 470.97 387.85 l S 470.97 270.11 m 473.54 270.11 l S 470.97 289.73 m 473.54 289.73 l S 470.97 309.35 m 473.54 309.35 l S 470.97 328.98 m 473.54 328.98 l S 470.97 348.60 m 473.54 348.60 l S 470.97 368.22 m 473.54 368.22 l S 470.97 387.85 m 473.54 387.85 l S BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 265.55 Tm (-3) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 285.17 Tm (-2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 304.79 Tm (-1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 326.75 Tm (0) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 346.38 Tm (1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 366.00 Tm (2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 459.56 385.62 Tm (3) Tj ET 470.97 393.03 m 470.97 264.47 l 628.04 264.47 l S BT /F4 1 Tf 12.00 0.00 -0.00 12.00 470.32 233.11 Tm [(Quantiles of Standard Nor) -25 (mal)] TJ ET BT /F2 1 Tf 0.00 12.00 -12.00 0.00 449.76 385.22 Tm (R) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 451.96 393.88 Tm (1) Tj ET Q q 38.97 48.47 157.08 128.56 re W n Q q 38.97 48.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 43.00 69.15 m 46.57 72.71 l S 43.00 72.71 m 46.57 69.15 l S 60.95 82.49 m 64.51 86.05 l S 60.95 86.05 m 64.51 82.49 l S 70.80 92.76 m 74.37 96.33 l S 70.80 96.33 m 74.37 92.76 l S 78.07 95.02 m 81.64 98.59 l S 78.07 98.59 m 81.64 95.02 l S 84.05 98.17 m 87.61 101.74 l S 84.05 101.74 m 87.61 98.17 l S 89.25 98.82 m 92.81 102.39 l S 89.25 102.39 m 92.81 98.82 l S 93.93 99.37 m 97.50 102.93 l S 93.93 102.93 m 97.50 99.37 l S 98.27 99.49 m 101.84 103.05 l S 98.27 103.05 m 101.84 99.49 l S 102.37 102.56 m 105.93 106.13 l S 102.37 106.13 m 105.93 102.56 l S 106.29 104.04 m 109.86 107.60 l S 106.29 107.60 m 109.86 104.04 l S 110.11 107.69 m 113.67 111.25 l S 110.11 111.25 m 113.67 107.69 l S 113.86 107.82 m 117.42 111.38 l S 113.86 111.38 m 117.42 107.82 l S 117.59 110.35 m 121.15 113.91 l S 117.59 113.91 m 121.15 110.35 l S 121.34 112.95 m 124.90 116.52 l S 121.34 116.52 m 124.90 112.95 l S 125.15 113.62 m 128.72 117.19 l S 125.15 117.19 m 128.72 113.62 l S 129.08 116.93 m 132.64 120.49 l S 129.08 120.49 m 132.64 116.93 l S 133.17 117.19 m 136.74 120.75 l S 133.17 120.75 m 136.74 117.19 l S 137.51 123.85 m 141.08 127.41 l S 137.51 127.41 m 141.08 123.85 l S 142.20 124.55 m 145.76 128.12 l S 142.20 128.12 m 145.76 124.55 l S 147.40 127.31 m 150.96 130.87 l S 147.40 130.87 m 150.96 127.31 l S 153.37 127.88 m 156.93 131.44 l S 153.37 131.44 m 156.93 127.88 l S 160.64 137.17 m 164.21 140.74 l S 160.64 140.74 m 164.21 137.17 l S 170.49 137.31 m 174.06 140.87 l S 170.49 140.87 m 174.06 137.31 l S 188.44 162.21 m 192.01 165.77 l S 188.44 165.77 m 192.01 162.21 l S Q q 0.00 0.00 216.00 216.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 10.00 0.00 -0.00 10.00 83.04 192.93 Tm (NM_000024_at) Tj ET Q q 38.97 48.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 42.92 53.23 m 46.65 53.23 l S 60.87 66.59 m 64.60 66.59 l S 70.72 81.54 m 74.45 81.54 l S 77.99 83.88 m 81.72 83.88 l S 83.97 90.49 m 87.70 90.49 l S 89.16 92.08 m 92.89 92.08 l S 93.85 94.67 m 97.58 94.67 l S 98.19 97.65 m 101.92 97.65 l S 102.28 99.45 m 106.01 99.45 l S 106.21 100.60 m 109.94 100.60 l S 110.02 102.04 m 113.75 102.04 l S 113.77 103.95 m 117.50 103.95 l S 117.50 107.39 m 121.23 107.39 l S 121.26 108.23 m 124.99 108.23 l S 125.07 109.48 m 128.80 109.48 l S 128.99 112.61 m 132.73 112.61 l S 133.09 115.25 m 136.82 115.25 l S 137.43 116.81 m 141.16 116.81 l S 142.12 119.58 m 145.85 119.58 l S 147.31 122.49 m 151.04 122.49 l S 153.29 127.08 m 157.02 127.08 l S 160.56 127.42 m 164.29 127.42 l S 170.41 132.00 m 174.14 132.00 l S 188.36 137.94 m 192.09 137.94 l S 42.92 87.50 m 46.65 87.50 l S 60.87 94.06 m 64.60 94.06 l S 70.72 96.75 m 74.45 96.75 l S 77.99 102.17 m 81.72 102.17 l S 83.97 103.89 m 87.70 103.89 l S 89.16 105.78 m 92.89 105.78 l S 93.85 106.74 m 97.58 106.74 l S 98.19 109.19 m 101.92 109.19 l S 102.28 110.73 m 106.01 110.73 l S 106.21 113.73 m 109.94 113.73 l S 110.02 116.12 m 113.75 116.12 l S 113.77 117.36 m 117.50 117.36 l S 117.50 119.54 m 121.23 119.54 l S 121.26 122.20 m 124.99 122.20 l S 125.07 124.78 m 128.80 124.78 l S 128.99 126.52 m 132.73 126.52 l S 133.09 130.54 m 136.82 130.54 l S 137.43 132.20 m 141.16 132.20 l S 142.12 134.81 m 145.85 134.81 l S 147.31 137.79 m 151.04 137.79 l S 153.29 142.05 m 157.02 142.05 l S 160.56 146.65 m 164.29 146.65 l S 170.41 151.78 m 174.14 151.78 l S 188.36 172.27 m 192.09 172.27 l S Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 42.53 48.47 m 192.48 48.47 l S 42.53 48.47 m 42.53 49.76 l S 46.10 48.47 m 46.10 49.76 l S 49.67 48.47 m 49.67 49.76 l S 53.24 48.47 m 53.24 49.76 l S 56.81 48.47 m 56.81 49.76 l S 60.38 48.47 m 60.38 49.76 l S 63.95 48.47 m 63.95 49.76 l S 67.52 48.47 m 67.52 49.76 l S 71.09 48.47 m 71.09 49.76 l S 74.66 48.47 m 74.66 49.76 l S 78.23 48.47 m 78.23 49.76 l S 81.80 48.47 m 81.80 49.76 l S 85.37 48.47 m 85.37 49.76 l S 88.94 48.47 m 88.94 49.76 l S 92.51 48.47 m 92.51 49.76 l S 96.08 48.47 m 96.08 49.76 l S 99.65 48.47 m 99.65 49.76 l S 103.22 48.47 m 103.22 49.76 l S 106.79 48.47 m 106.79 49.76 l S 110.36 48.47 m 110.36 49.76 l S 113.93 48.47 m 113.93 49.76 l S 117.50 48.47 m 117.50 49.76 l S 121.07 48.47 m 121.07 49.76 l S 124.64 48.47 m 124.64 49.76 l S 128.21 48.47 m 128.21 49.76 l S 131.78 48.47 m 131.78 49.76 l S 135.36 48.47 m 135.36 49.76 l S 138.93 48.47 m 138.93 49.76 l S 142.50 48.47 m 142.50 49.76 l S 146.07 48.47 m 146.07 49.76 l S 149.64 48.47 m 149.64 49.76 l S 153.21 48.47 m 153.21 49.76 l S 156.78 48.47 m 156.78 49.76 l S 160.35 48.47 m 160.35 49.76 l S 163.92 48.47 m 163.92 49.76 l S 167.49 48.47 m 167.49 49.76 l S 171.06 48.47 m 171.06 49.76 l S 174.63 48.47 m 174.63 49.76 l S 178.20 48.47 m 178.20 49.76 l S 181.77 48.47 m 181.77 49.76 l S 185.34 48.47 m 185.34 49.76 l S 188.91 48.47 m 188.91 49.76 l S 192.48 48.47 m 192.48 49.76 l S 46.10 48.47 m 188.91 48.47 l S 46.10 48.47 m 46.10 51.04 l S 63.95 48.47 m 63.95 51.04 l S 81.80 48.47 m 81.80 51.04 l S 99.65 48.47 m 99.65 51.04 l S 117.50 48.47 m 117.50 51.04 l S 135.36 48.47 m 135.36 51.04 l S 153.21 48.47 m 153.21 51.04 l S 171.06 48.47 m 171.06 51.04 l S 188.91 48.47 m 188.91 51.04 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 8.00 0.00 -0.00 8.00 38.20 31.36 Tm (-2.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 73.91 31.36 Tm (-1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 111.94 31.36 Tm (0.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 129.80 31.36 Tm (0.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 147.65 31.36 Tm (1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 165.50 31.36 Tm (1.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 183.35 31.36 Tm (2.0) Tj ET 38.97 50.18 m 38.97 175.77 l S 38.97 50.18 m 40.25 50.18 l S 38.97 54.11 m 40.25 54.11 l S 38.97 58.03 m 40.25 58.03 l S 38.97 61.96 m 40.25 61.96 l S 38.97 65.88 m 40.25 65.88 l S 38.97 69.81 m 40.25 69.81 l S 38.97 73.73 m 40.25 73.73 l S 38.97 77.66 m 40.25 77.66 l S 38.97 81.58 m 40.25 81.58 l S 38.97 85.51 m 40.25 85.51 l S 38.97 89.43 m 40.25 89.43 l S 38.97 93.35 m 40.25 93.35 l S 38.97 97.28 m 40.25 97.28 l S 38.97 101.20 m 40.25 101.20 l S 38.97 105.13 m 40.25 105.13 l S 38.97 109.05 m 40.25 109.05 l S 38.97 112.98 m 40.25 112.98 l S 38.97 116.90 m 40.25 116.90 l S 38.97 120.83 m 40.25 120.83 l S 38.97 124.75 m 40.25 124.75 l S 38.97 128.68 m 40.25 128.68 l S 38.97 132.60 m 40.25 132.60 l S 38.97 136.53 m 40.25 136.53 l S 38.97 140.45 m 40.25 140.45 l S 38.97 144.38 m 40.25 144.38 l S 38.97 148.30 m 40.25 148.30 l S 38.97 152.22 m 40.25 152.22 l S 38.97 156.15 m 40.25 156.15 l S 38.97 160.07 m 40.25 160.07 l S 38.97 164.00 m 40.25 164.00 l S 38.97 167.92 m 40.25 167.92 l S 38.97 171.85 m 40.25 171.85 l S 38.97 175.77 m 40.25 175.77 l S 38.97 54.11 m 38.97 171.85 l S 38.97 54.11 m 41.54 54.11 l S 38.97 73.73 m 41.54 73.73 l S 38.97 93.35 m 41.54 93.35 l S 38.97 112.98 m 41.54 112.98 l S 38.97 132.60 m 41.54 132.60 l S 38.97 152.22 m 41.54 152.22 l S 38.97 171.85 m 41.54 171.85 l S BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 49.55 Tm (-3) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 69.17 Tm (-2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 88.79 Tm (-1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 110.75 Tm (0) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 130.38 Tm (1) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 150.00 Tm (2) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 27.56 169.62 Tm (3) Tj ET 38.97 177.03 m 38.97 48.47 l 196.04 48.47 l S BT /F4 1 Tf 12.00 0.00 -0.00 12.00 38.32 17.11 Tm [(Quantiles of Standard Nor) -25 (mal)] TJ ET BT /F2 1 Tf 0.00 12.00 -12.00 0.00 17.76 169.22 Tm (R) Tj ET BT /F2 1 Tf 0.00 8.00 -8.00 0.00 19.96 177.88 Tm (1) Tj ET Q q 254.97 48.47 157.08 128.56 re W n Q q 254.97 48.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 259.00 72.36 m 262.57 75.92 l S 259.00 75.92 m 262.57 72.36 l S 276.95 79.69 m 280.51 83.26 l S 276.95 83.26 m 280.51 79.69 l S 286.80 84.07 m 290.37 87.63 l S 286.80 87.63 m 290.37 84.07 l S 294.07 90.45 m 297.64 94.02 l S 294.07 94.02 m 297.64 90.45 l S 300.05 99.74 m 303.61 103.30 l S 300.05 103.30 m 303.61 99.74 l S 305.25 100.76 m 308.81 104.33 l S 305.25 104.33 m 308.81 100.76 l S 309.93 101.33 m 313.50 104.89 l S 309.93 104.89 m 313.50 101.33 l S 314.27 103.05 m 317.84 106.61 l S 314.27 106.61 m 317.84 103.05 l S 318.37 103.86 m 321.93 107.42 l S 318.37 107.42 m 321.93 103.86 l S 322.29 104.16 m 325.86 107.72 l S 322.29 107.72 m 325.86 104.16 l S 326.11 107.52 m 329.67 111.08 l S 326.11 111.08 m 329.67 107.52 l S 329.86 108.13 m 333.42 111.69 l S 329.86 111.69 m 333.42 108.13 l S 333.59 109.47 m 337.15 113.04 l S 333.59 113.04 m 337.15 109.47 l S 337.34 115.35 m 340.90 118.92 l S 337.34 118.92 m 340.90 115.35 l S 341.15 117.01 m 344.72 120.57 l S 341.15 120.57 m 344.72 117.01 l S 345.08 117.09 m 348.64 120.66 l S 345.08 120.66 m 348.64 117.09 l S 349.17 117.26 m 352.74 120.82 l S 349.17 120.82 m 352.74 117.26 l S 353.51 121.78 m 357.08 125.35 l S 353.51 125.35 m 357.08 121.78 l S 358.20 122.26 m 361.76 125.83 l S 358.20 125.83 m 361.76 122.26 l S 363.40 127.70 m 366.96 131.27 l S 363.40 131.27 m 366.96 127.70 l S 369.37 129.55 m 372.93 133.12 l S 369.37 133.12 m 372.93 129.55 l S 376.64 134.24 m 380.21 137.80 l S 376.64 137.80 m 380.21 134.24 l S 386.49 150.54 m 390.06 154.10 l S 386.49 154.10 m 390.06 150.54 l S 404.44 151.33 m 408.01 154.89 l S 404.44 154.89 m 408.01 151.33 l S Q q 216.00 0.00 216.00 216.00 re W n BT 0.000 0.000 0.000 rg /F3 1 Tf 10.00 0.00 -0.00 10.00 299.04 192.93 Tm (NM_000025_at) Tj ET Q q 254.97 48.47 157.08 128.56 re W n 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 258.92 53.23 m 262.65 53.23 l S 276.87 66.59 m 280.60 66.59 l S 286.72 81.54 m 290.45 81.54 l S 293.99 83.88 m 297.72 83.88 l S 299.97 90.49 m 303.70 90.49 l S 305.16 92.08 m 308.89 92.08 l S 309.85 94.67 m 313.58 94.67 l S 314.19 97.65 m 317.92 97.65 l S 318.28 99.45 m 322.01 99.45 l S 322.21 100.60 m 325.94 100.60 l S 326.02 102.04 m 329.75 102.04 l S 329.77 103.95 m 333.50 103.95 l S 333.50 107.39 m 337.23 107.39 l S 337.26 108.23 m 340.99 108.23 l S 341.07 109.48 m 344.80 109.48 l S 344.99 112.61 m 348.73 112.61 l S 349.09 115.25 m 352.82 115.25 l S 353.43 116.81 m 357.16 116.81 l S 358.12 119.58 m 361.85 119.58 l S 363.31 122.49 m 367.04 122.49 l S 369.29 127.08 m 373.02 127.08 l S 376.56 127.42 m 380.29 127.42 l S 386.41 132.00 m 390.14 132.00 l S 404.36 137.94 m 408.09 137.94 l S 258.92 87.50 m 262.65 87.50 l S 276.87 94.06 m 280.60 94.06 l S 286.72 96.75 m 290.45 96.75 l S 293.99 102.17 m 297.72 102.17 l S 299.97 103.89 m 303.70 103.89 l S 305.16 105.78 m 308.89 105.78 l S 309.85 106.74 m 313.58 106.74 l S 314.19 109.19 m 317.92 109.19 l S 318.28 110.73 m 322.01 110.73 l S 322.21 113.73 m 325.94 113.73 l S 326.02 116.12 m 329.75 116.12 l S 329.77 117.36 m 333.50 117.36 l S 333.50 119.54 m 337.23 119.54 l S 337.26 122.20 m 340.99 122.20 l S 341.07 124.78 m 344.80 124.78 l S 344.99 126.52 m 348.73 126.52 l S 349.09 130.54 m 352.82 130.54 l S 353.43 132.20 m 357.16 132.20 l S 358.12 134.81 m 361.85 134.81 l S 363.31 137.79 m 367.04 137.79 l S 369.29 142.05 m 373.02 142.05 l S 376.56 146.65 m 380.29 146.65 l S 386.41 151.78 m 390.14 151.78 l S 404.36 172.27 m 408.09 172.27 l S Q q 0.000 0.000 0.000 RG 0.75 w [] 0 d 1 J 1 j 10.00 M 258.53 48.47 m 408.48 48.47 l S 258.53 48.47 m 258.53 49.76 l S 262.10 48.47 m 262.10 49.76 l S 265.67 48.47 m 265.67 49.76 l S 269.24 48.47 m 269.24 49.76 l S 272.81 48.47 m 272.81 49.76 l S 276.38 48.47 m 276.38 49.76 l S 279.95 48.47 m 279.95 49.76 l S 283.52 48.47 m 283.52 49.76 l S 287.09 48.47 m 287.09 49.76 l S 290.66 48.47 m 290.66 49.76 l S 294.23 48.47 m 294.23 49.76 l S 297.80 48.47 m 297.80 49.76 l S 301.37 48.47 m 301.37 49.76 l S 304.94 48.47 m 304.94 49.76 l S 308.51 48.47 m 308.51 49.76 l S 312.08 48.47 m 312.08 49.76 l S 315.65 48.47 m 315.65 49.76 l S 319.22 48.47 m 319.22 49.76 l S 322.79 48.47 m 322.79 49.76 l S 326.36 48.47 m 326.36 49.76 l S 329.93 48.47 m 329.93 49.76 l S 333.50 48.47 m 333.50 49.76 l S 337.07 48.47 m 337.07 49.76 l S 340.64 48.47 m 340.64 49.76 l S 344.21 48.47 m 344.21 49.76 l S 347.78 48.47 m 347.78 49.76 l S 351.36 48.47 m 351.36 49.76 l S 354.93 48.47 m 354.93 49.76 l S 358.50 48.47 m 358.50 49.76 l S 362.07 48.47 m 362.07 49.76 l S 365.64 48.47 m 365.64 49.76 l S 369.21 48.47 m 369.21 49.76 l S 372.78 48.47 m 372.78 49.76 l S 376.35 48.47 m 376.35 49.76 l S 379.92 48.47 m 379.92 49.76 l S 383.49 48.47 m 383.49 49.76 l S 387.06 48.47 m 387.06 49.76 l S 390.63 48.47 m 390.63 49.76 l S 394.20 48.47 m 394.20 49.76 l S 397.77 48.47 m 397.77 49.76 l S 401.34 48.47 m 401.34 49.76 l S 404.91 48.47 m 404.91 49.76 l S 408.48 48.47 m 408.48 49.76 l S 262.10 48.47 m 404.91 48.47 l S 262.10 48.47 m 262.10 51.04 l S 279.95 48.47 m 279.95 51.04 l S 297.80 48.47 m 297.80 51.04 l S 315.65 48.47 m 315.65 51.04 l S 333.50 48.47 m 333.50 51.04 l S 351.36 48.47 m 351.36 51.04 l S 369.21 48.47 m 369.21 51.04 l S 387.06 48.47 m 387.06 51.04 l S 404.91 48.47 m 404.91 51.04 l S BT 0.000 0.000 0.000 rg /F2 1 Tf 8.00 0.00 -0.00 8.00 254.20 31.36 Tm (-2.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 289.91 31.36 Tm (-1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 327.94 31.36 Tm (0.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 345.80 31.36 Tm (0.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 363.65 31.36 Tm (1.0) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 381.50 31.36 Tm (1.5) Tj ET BT /F2 1 Tf 8.00 0.00 -0.00 8.00 399.35 31.36 Tm (2.0) Tj ET 254.97 50.18 m 254.97 175.77 l S 254.97 50.18 m 256.25 50.18 l S 254.97 54.11 m 256.25 54.11 l S 254.97 58.03 m 256.25 58.03 l S 254.97 61.96 m 256.25 61.96 l S 254.97 65.88 m 256.25 65.88 l S 254.97 69.81 m 256.25 69.81 l S 254.97 73.73 m 256.25 73.73 l S 254.97 77.66 m 256.25 77.66 l S 254.97 81.58 m 256.25 81.58 l S 254.97 85.51 m 256.25 85.51 l S 254.97 89.43 m 256.25 89.43 l S 254.97 93.35 m 256.25 93.35 l S 254.97 97.28 m 256.25 97.28 l S 254.97 101.20 m 256.25 101.20 l S 254.97 105.13 m 256.25 105.13 l S 254.97 109.05 m 256.25 109.05 l S 254.97 112.98 m 256.25 112.98 l S 254.97 116.90 m 256.25 116.90 l S 254.97 120.83 m 256.25 120.83 l S 254.97 124.75 m 256.25 124.75 l S 254.97 128.68 m 256.25 128.68 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