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/Prev 39 0 R /Next 47 0 R >> endobj 39 0 obj << /Title 40 0 R /A 37 0 R /Parent 1007 0 R /Prev 35 0 R /Next 43 0 R >> endobj 35 0 obj << /Title 36 0 R /A 33 0 R /Parent 1007 0 R /Prev 31 0 R /Next 39 0 R >> endobj 31 0 obj << /Title 32 0 R /A 29 0 R /Parent 1007 0 R /Prev 27 0 R /Next 35 0 R >> endobj 27 0 obj << /Title 28 0 R /A 25 0 R /Parent 1007 0 R /Prev 23 0 R /Next 31 0 R >> endobj 23 0 obj << /Title 24 0 R /A 21 0 R /Parent 1007 0 R /Prev 19 0 R /Next 27 0 R >> endobj 19 0 obj << /Title 20 0 R /A 17 0 R /Parent 1007 0 R /Prev 15 0 R /Next 23 0 R >> endobj 15 0 obj << /Title 16 0 R /A 13 0 R /Parent 1007 0 R /Prev 11 0 R /Next 19 0 R >> endobj 11 0 obj << /Title 12 0 R /A 9 0 R /Parent 1007 0 R /Prev 7 0 R /Next 15 0 R >> endobj 7 0 obj << /Title 8 0 R /A 5 0 R /Parent 1007 0 R /Prev 3 0 R /Next 11 0 R >> endobj 3 0 obj << /Title 4 0 R /A 1 0 R /Parent 1007 0 R /Next 7 0 R >> endobj 1008 0 obj << /Names [(Doc-Start) 166 0 R (Item.1) 481 0 R (Item.2) 482 0 R (Item.3) 483 0 R (Item.4) 484 0 R (Item.5) 485 0 R] /Limits [(Doc-Start) (Item.5)] >> endobj 1009 0 obj << /Names [(Rfn.GenRegRes) 312 0 R (Rfn.GenRegRes.Rdash.class) 308 0 R (Rfn.GenRegRes.Rdash.class.1) 22 0 R (Rfn.MLearn) 561 0 R (Rfn.MLearn,formula,MSnSet,clusteringSchema,missing.Rdash.method) 548 0 R (Rfn.MLearn,formula,MSnSet,learnerSchema,numeric.Rdash.method) 549 0 R] /Limits [(Rfn.GenRegRes) (Rfn.MLearn,formula,MSnSet,learnerSchema,numeric.Rdash.method)] >> endobj 1010 0 obj << /Names [(Rfn.MLearn,formula,MSnSet,learnerSchema,xvalSpec.Rdash.method) 550 0 R (Rfn.MLearn.Rdash.methods) 547 0 R (Rfn.MLearn.Rdash.methods.1) 74 0 R (Rfn.MLearnMSnSet) 551 0 R (Rfn.MSnSet.Rdash.class) 331 0 R (Rfn.MSnSetMLean) 552 0 R] /Limits [(Rfn.MLearn,formula,MSnSet,learnerSchema,xvalSpec.Rdash.method) (Rfn.MSnSetMLean)] >> endobj 1011 0 obj << /Names [(Rfn.Synapter) 472 0 R (Rfn.addLegend) 212 0 R (Rfn.addLegend.1) 2 0 R (Rfn.addMarkers) 251 0 R (Rfn.addMarkers.1) 6 0 R (Rfn.chi2) 263 0 R] /Limits [(Rfn.Synapter) (Rfn.chi2)] >> endobj 1012 0 obj << /Names [(Rfn.chi2,matrix,matrix.Rdash.method) 264 0 R (Rfn.chi2,matrix,numeric.Rdash.method) 265 0 R (Rfn.chi2,numeric,matrix.Rdash.method) 266 0 R (Rfn.chi2,numeric,numeric.Rdash.method) 267 0 R (Rfn.chi2.Rdash.methods) 262 0 R (Rfn.chi2.Rdash.methods.1) 10 0 R] /Limits [(Rfn.chi2,matrix,matrix.Rdash.method) (Rfn.chi2.Rdash.methods.1)] >> endobj 1013 0 obj << /Names [(Rfn.chol2inv) 645 0 R (Rfn.class:GenRegRes) 309 0 R (Rfn.cmdscale) 694 0 R (Rfn.empPvalues) 281 0 R (Rfn.empPvalues.1) 14 0 R (Rfn.estimateMasterFdr) 489 0 R] /Limits [(Rfn.chol2inv) (Rfn.estimateMasterFdr)] >> endobj 1014 0 obj << /Names [(Rfn.exprsToRatios) 303 0 R (Rfn.exprsToRatios,MSnSet.Rdash.method) 304 0 R (Rfn.exprsToRatios.Rdash.methods) 302 0 R (Rfn.exprsToRatios.Rdash.methods.1) 18 0 R (Rfn.f1Count) 310 0 R (Rfn.f1Count,GenRegRes.Rdash.method) 311 0 R] /Limits [(Rfn.exprsToRatios) (Rfn.f1Count,GenRegRes.Rdash.method)] >> endobj 1015 0 obj << /Names [(Rfn.filterNA) 683 0 R (Rfn.getF1Scores) 313 0 R (Rfn.getF1Scores,GenRegRes.Rdash.method) 314 0 R (Rfn.getMarkers) 350 0 R (Rfn.getMarkers.1) 26 0 R (Rfn.getParams) 315 0 R] /Limits [(Rfn.filterNA) (Rfn.getParams)] >> endobj 1016 0 obj << /Names [(Rfn.getParams,ClustRegRes.Rdash.method) 832 0 R (Rfn.getParams,GenRegRes.Rdash.method) 316 0 R (Rfn.getPredictions) 364 0 R (Rfn.getPredictions.1) 30 0 R (Rfn.getRegularisedParams) 317 0 R (Rfn.getRegularisedParams,GenRegRes.Rdash.method) 318 0 R] /Limits [(Rfn.getParams,ClustRegRes.Rdash.method) (Rfn.getRegularisedParams,GenRegRes.Rdash.method)] >> endobj 1017 0 obj << /Names [(Rfn.getRegularizedParams) 319 0 R (Rfn.getRegularizedParams,GenRegRes.Rdash.method) 320 0 R (Rfn.getSeed) 321 0 R (Rfn.getSeed,GenRegRes.Rdash.method) 322 0 R (Rfn.getStockcol) 370 0 R (Rfn.getStockcol.1) 34 0 R] /Limits [(Rfn.getRegularizedParams) (Rfn.getStockcol.1)] >> endobj 1018 0 obj << /Names [(Rfn.getStockpch) 371 0 R (Rfn.getUnknowncol) 372 0 R (Rfn.getUnknownpch) 373 0 R (Rfn.getWarnings) 323 0 R (Rfn.getWarnings,GenRegRes.Rdash.method) 324 0 R (Rfn.ginv) 646 0 R] /Limits [(Rfn.getStockpch) (Rfn.ginv)] >> endobj 1019 0 obj << /Names [(Rfn.identify) 695 0 R (Rfn.knn) 403 0 R (Rfn.knnClassification) 396 0 R (Rfn.knnClassification.1) 38 0 R (Rfn.knnOptimisation) 402 0 R (Rfn.knnOptimisation.1) 42 0 R] /Limits [(Rfn.identify) (Rfn.knnOptimisation.1)] >> endobj 1020 0 obj << /Names [(Rfn.knnOptimization) 412 0 R (Rfn.knnPrediction) 397 0 R (Rfn.knnRegularisation) 332 0 R (Rfn.ksvm) 437 0 R (Rfn.ksvmClassification) 428 0 R (Rfn.ksvmClassification.1) 46 0 R] /Limits [(Rfn.knnOptimization) (Rfn.ksvmClassification.1)] >> endobj 1021 0 obj << /Names [(Rfn.ksvmOptimisation) 436 0 R (Rfn.ksvmOptimisation.1) 50 0 R (Rfn.ksvmOptimization) 446 0 R (Rfn.ksvmPrediction) 429 0 R (Rfn.ksvmRegularisation) 447 0 R (Rfn.legend) 257 0 R] /Limits [(Rfn.ksvmOptimisation) (Rfn.legend)] >> endobj 1022 0 obj << /Names [(Rfn.levelPlot) 325 0 R (Rfn.levelPlot,ClustRegRes.Rdash.method) 833 0 R (Rfn.levelPlot,GenRegRes.Rdash.method) 326 0 R (Rfn.lopims) 466 0 R (Rfn.lopims.1) 54 0 R (Rfn.makeMaster) 490 0 R] /Limits [(Rfn.levelPlot) (Rfn.makeMaster)] >> endobj 1023 0 obj << /Names [(Rfn.makeNaData) 494 0 R (Rfn.makeNaData.1) 58 0 R (Rfn.makeNaData2) 495 0 R (Rfn.markerSet) 507 0 R (Rfn.markerSet.1) 62 0 R (Rfn.minClassScore) 519 0 R] /Limits [(Rfn.makeNaData) (Rfn.minClassScore)] >> endobj 1024 0 obj << /Names [(Rfn.minClassScore.1) 66 0 R (Rfn.minMarkers) 359 0 R (Rfn.minMarkers.1) 70 0 R (Rfn.naiveBayes) 577 0 R (Rfn.nbClassification) 556 0 R (Rfn.nbClassification.1) 78 0 R] /Limits [(Rfn.minClassScore.1) (Rfn.nbClassification.1)] >> endobj 1025 0 obj << /Names [(Rfn.nbOptimisation) 572 0 R (Rfn.nbOptimisation.1) 82 0 R (Rfn.nbOptimization) 573 0 R (Rfn.nbPrediction) 557 0 R (Rfn.nbRegularisation) 574 0 R (Rfn.nnet) 610 0 R] /Limits [(Rfn.nbOptimisation) (Rfn.nnet)] >> endobj 1026 0 obj << /Names [(Rfn.nnetClassification) 592 0 R (Rfn.nnetClassification.1) 86 0 R (Rfn.nnetOptimisation) 605 0 R (Rfn.nnetOptimisation.1) 90 0 R (Rfn.nnetOptimization) 606 0 R (Rfn.nnetPrediction) 593 0 R] /Limits [(Rfn.nnetClassification) (Rfn.nnetPrediction)] >> endobj 1027 0 obj << /Names [(Rfn.nnetRegularisation) 607 0 R (Rfn.perTurboClassification) 626 0 R (Rfn.perTurboClassification.1) 94 0 R (Rfn.perTurboOptimisation) 644 0 R (Rfn.perTurboOptimisation.1) 98 0 R (Rfn.perTurboOptimization) 658 0 R] /Limits [(Rfn.nnetRegularisation) (Rfn.perTurboOptimization)] >> endobj 1028 0 obj << /Names [(Rfn.phenoDisco) 670 0 R (Rfn.phenoDisco.1) 102 0 R (Rfn.plot) 724 0 R (Rfn.plot,ClustRegRes,missing.Rdash.method) 834 0 R (Rfn.plot,GenRegRes,missing.Rdash.method) 327 0 R (Rfn.plot2D) 243 0 R] /Limits [(Rfn.phenoDisco) (Rfn.plot2D)] >> endobj 1029 0 obj << /Names [(Rfn.plot2D.1) 106 0 R (Rfn.plotDist) 705 0 R (Rfn.plotDist.1) 110 0 R (Rfn.plsda) 737 0 R (Rfn.plsdaClassification) 720 0 R (Rfn.plsdaClassification.1) 114 0 R] /Limits [(Rfn.plot2D.1) (Rfn.plsdaClassification.1)] >> endobj 1030 0 obj << /Names [(Rfn.plsdaOptimisation) 734 0 R (Rfn.plsdaOptimisation.1) 118 0 R (Rfn.plsdaOptimization) 735 0 R (Rfn.plsdaPrediction) 721 0 R (Rfn.plsdaRegularisation) 334 0 R (Rfn.prcomp) 693 0 R] /Limits [(Rfn.plsdaOptimisation) (Rfn.prcomp)] >> endobj 1031 0 obj << /Names [(Rfn.randomForest) 772 0 R (Rfn.rfClassification) 753 0 R (Rfn.rfClassification.1) 122 0 R (Rfn.rfOptimisation) 767 0 R (Rfn.rfOptimisation.1) 126 0 R (Rfn.rfOptimization) 768 0 R] /Limits [(Rfn.randomForest) (Rfn.rfOptimization)] >> endobj 1032 0 obj << /Names [(Rfn.rfPrediction) 754 0 R (Rfn.rfRegularisation) 769 0 R (Rfn.setStockcol) 374 0 R (Rfn.setStockpch) 375 0 R (Rfn.setUnknowncol) 376 0 R (Rfn.setUnknownpch) 377 0 R] /Limits [(Rfn.rfPrediction) (Rfn.setUnknownpch)] >> endobj 1033 0 obj << /Names [(Rfn.show,ClustRegRes.Rdash.method) 835 0 R (Rfn.show,GenRegRes.Rdash.method) 328 0 R (Rfn.solve) 647 0 R (Rfn.svd) 648 0 R (Rfn.svm) 805 0 R (Rfn.svmClassification) 787 0 R] /Limits [(Rfn.show,ClustRegRes.Rdash.method) (Rfn.svmClassification)] >> endobj 1034 0 obj << /Names [(Rfn.svmClassification.1) 130 0 R (Rfn.svmOptimisation) 800 0 R (Rfn.svmOptimisation.1) 134 0 R (Rfn.svmOptimization) 801 0 R (Rfn.svmPrediction) 788 0 R (Rfn.svmRegularisation) 333 0 R] /Limits [(Rfn.svmClassification.1) (Rfn.svmRegularisation)] >> endobj 1035 0 obj << /Names [(Rfn.synapter) 471 0 R (Rfn.synergise) 470 0 R (Rfn.testMarkers) 358 0 R (Rfn.testMarkers.1) 138 0 R (Rfn.undocumented) 831 0 R (Rfn.undocumented.1) 142 0 R] /Limits [(Rfn.synapter) (Rfn.undocumented.1)] >> endobj 1036 0 obj << /Names [(Rfn.whichNA) 496 0 R (Rfn.xvalSpec) 560 0 R (chapter*.1) 167 0 R (index.0) 146 0 R (page.1) 165 0 R (page.10) 382 0 R] /Limits [(Rfn.whichNA) (page.10)] >> endobj 1037 0 obj << /Names [(page.11) 216 0 R (page.12) 217 0 R (page.13) 218 0 R (page.14) 219 0 R (page.15) 220 0 R (page.16) 479 0 R] /Limits [(page.11) (page.16)] >> endobj 1038 0 obj << /Names [(page.17) 221 0 R (page.18) 222 0 R (page.19) 223 0 R (page.2) 174 0 R (page.20) 224 0 R (page.21) 225 0 R] /Limits [(page.17) (page.21)] >> endobj 1039 0 obj << /Names [(page.22) 226 0 R (page.23) 227 0 R (page.24) 228 0 R (page.25) 229 0 R (page.26) 638 0 R (page.27) 230 0 R] /Limits [(page.22) (page.27)] >> endobj 1040 0 obj << /Names [(page.28) 231 0 R (page.29) 232 0 R (page.3) 175 0 R (page.30) 690 0 R (page.31) 233 0 R (page.32) 234 0 R] /Limits [(page.28) (page.32)] >> endobj 1041 0 obj << /Names [(page.33) 235 0 R (page.34) 236 0 R (page.35) 237 0 R (page.36) 238 0 R (page.37) 239 0 R (page.38) 240 0 R] /Limits [(page.33) (page.38)] >> endobj 1042 0 obj << /Names [(page.39) 241 0 R (page.4) 176 0 R (page.40) 242 0 R (page.41) 951 0 R (page.42) 956 0 R (page.5) 177 0 R] /Limits [(page.39) (page.5)] >> endobj 1043 0 obj << /Names [(page.6) 178 0 R (page.7) 338 0 R (page.8) 179 0 R (page.9) 180 0 R (section*.10) 254 0 R (section*.100) 522 0 R] /Limits [(page.6) (section*.100)] >> endobj 1044 0 obj << /Names [(section*.101) 529 0 R (section*.102) 530 0 R (section*.103) 531 0 R (section*.104) 532 0 R (section*.105) 533 0 R (section*.106) 534 0 R] /Limits [(section*.101) (section*.106)] >> endobj 1045 0 obj << /Names [(section*.107) 535 0 R (section*.108) 536 0 R (section*.109) 546 0 R (section*.11) 255 0 R (section*.110) 553 0 R (section*.111) 554 0 R] /Limits [(section*.107) (section*.111)] >> endobj 1046 0 obj << /Names [(section*.112) 555 0 R (section*.113) 558 0 R (section*.114) 559 0 R (section*.115) 568 0 R (section*.116) 569 0 R (section*.117) 570 0 R] /Limits [(section*.112) (section*.117)] >> endobj 1047 0 obj << /Names [(section*.118) 571 0 R (section*.119) 575 0 R (section*.12) 256 0 R (section*.120) 576 0 R (section*.121) 588 0 R (section*.122) 589 0 R] /Limits [(section*.118) (section*.122)] >> endobj 1048 0 obj << /Names [(section*.123) 590 0 R (section*.124) 591 0 R (section*.125) 594 0 R (section*.126) 595 0 R (section*.127) 601 0 R (section*.128) 602 0 R] /Limits [(section*.123) (section*.128)] >> endobj 1049 0 obj << /Names [(section*.129) 603 0 R (section*.13) 268 0 R (section*.130) 604 0 R (section*.131) 608 0 R (section*.132) 609 0 R (section*.133) 622 0 R] /Limits [(section*.129) (section*.133)] >> endobj 1050 0 obj << /Names [(section*.134) 623 0 R (section*.135) 624 0 R (section*.136) 625 0 R (section*.137) 627 0 R (section*.138) 628 0 R (section*.139) 639 0 R] /Limits [(section*.134) (section*.139)] >> endobj 1051 0 obj << /Names [(section*.14) 276 0 R (section*.140) 640 0 R (section*.141) 641 0 R (section*.142) 642 0 R (section*.143) 643 0 R (section*.144) 659 0 R] /Limits [(section*.14) (section*.144)] >> endobj 1052 0 obj << /Names [(section*.145) 660 0 R (section*.146) 661 0 R (section*.147) 667 0 R (section*.148) 668 0 R (section*.149) 669 0 R (section*.15) 278 0 R] /Limits [(section*.145) (section*.15)] >> endobj 1053 0 obj << /Names [(section*.150) 671 0 R (section*.151) 672 0 R (section*.152) 673 0 R (section*.153) 677 0 R (section*.154) 678 0 R (section*.155) 679 0 R] /Limits [(section*.150) (section*.155)] >> endobj 1054 0 obj << /Names [(section*.156) 680 0 R (section*.157) 681 0 R (section*.158) 682 0 R (section*.159) 691 0 R (section*.16) 279 0 R (section*.160) 692 0 R] /Limits [(section*.156) (section*.160)] >> endobj 1055 0 obj << /Names [(section*.161) 701 0 R (section*.162) 702 0 R (section*.163) 703 0 R (section*.164) 704 0 R (section*.165) 706 0 R (section*.166) 707 0 R] /Limits [(section*.161) (section*.166)] >> endobj 1056 0 obj << /Names [(section*.167) 716 0 R (section*.168) 717 0 R (section*.169) 718 0 R (section*.17) 280 0 R (section*.170) 719 0 R (section*.171) 722 0 R] /Limits [(section*.167) (section*.171)] >> endobj 1057 0 obj << /Names [(section*.172) 723 0 R (section*.173) 730 0 R (section*.174) 731 0 R (section*.175) 732 0 R (section*.176) 733 0 R (section*.177) 736 0 R] /Limits [(section*.172) (section*.177)] >> endobj 1058 0 obj << /Names [(section*.178) 748 0 R (section*.179) 749 0 R (section*.18) 286 0 R (section*.180) 750 0 R (section*.181) 751 0 R (section*.182) 752 0 R] /Limits [(section*.178) (section*.182)] >> endobj 1059 0 obj << /Names [(section*.183) 755 0 R (section*.184) 756 0 R (section*.185) 763 0 R (section*.186) 764 0 R (section*.187) 765 0 R (section*.188) 766 0 R] /Limits [(section*.183) (section*.188)] >> endobj 1060 0 obj << /Names [(section*.189) 770 0 R (section*.19) 287 0 R (section*.190) 771 0 R (section*.191) 783 0 R (section*.192) 784 0 R (section*.193) 785 0 R] /Limits [(section*.189) (section*.193)] >> endobj 1061 0 obj << /Names [(section*.194) 786 0 R (section*.195) 789 0 R (section*.196) 790 0 R (section*.197) 796 0 R (section*.198) 797 0 R (section*.199) 798 0 R] /Limits [(section*.194) (section*.199)] >> endobj 1062 0 obj << /Names [(section*.2) 172 0 R (section*.20) 288 0 R (section*.200) 799 0 R (section*.201) 802 0 R (section*.202) 803 0 R (section*.203) 814 0 R] /Limits [(section*.2) (section*.203)] >> endobj 1063 0 obj << /Names [(section*.204) 815 0 R (section*.205) 816 0 R (section*.206) 817 0 R (section*.207) 818 0 R (section*.208) 819 0 R (section*.209) 820 0 R] /Limits [(section*.204) (section*.209)] >> endobj 1064 0 obj << /Names [(section*.21) 289 0 R (section*.210) 826 0 R (section*.211) 827 0 R (section*.212) 828 0 R (section*.213) 829 0 R (section*.214) 830 0 R] /Limits [(section*.21) (section*.214)] >> endobj 1065 0 obj << /Names [(section*.215) 836 0 R (section*.216) 837 0 R (section*.22) 290 0 R (section*.23) 291 0 R (section*.24) 292 0 R (section*.25) 293 0 R] /Limits [(section*.215) (section*.25)] >> endobj 1066 0 obj << /Names [(section*.26) 301 0 R (section*.27) 305 0 R (section*.28) 306 0 R (section*.29) 307 0 R (section*.3) 214 0 R (section*.30) 329 0 R] /Limits [(section*.26) (section*.30)] >> endobj 1067 0 obj << /Names [(section*.31) 330 0 R (section*.32) 339 0 R (section*.33) 340 0 R (section*.34) 341 0 R (section*.35) 342 0 R (section*.36) 351 0 R] /Limits [(section*.31) (section*.36)] >> endobj 1068 0 obj << /Names [(section*.37) 352 0 R (section*.38) 353 0 R (section*.39) 354 0 R (section*.4) 215 0 R (section*.40) 355 0 R (section*.41) 356 0 R] /Limits [(section*.37) (section*.41)] >> endobj 1069 0 obj << /Names [(section*.42) 357 0 R (section*.43) 365 0 R (section*.44) 366 0 R (section*.45) 367 0 R (section*.46) 368 0 R (section*.47) 369 0 R] /Limits [(section*.42) (section*.47)] >> endobj 1070 0 obj << /Names [(section*.48) 378 0 R (section*.49) 383 0 R (section*.5) 248 0 R (section*.50) 384 0 R (section*.51) 385 0 R (section*.52) 386 0 R] /Limits [(section*.48) (section*.52)] >> endobj 1071 0 obj << /Names [(section*.53) 395 0 R (section*.54) 398 0 R (section*.55) 399 0 R (section*.56) 400 0 R (section*.57) 401 0 R (section*.58) 410 0 R] /Limits [(section*.53) (section*.58)] >> endobj 1072 0 obj << /Names [(section*.59) 411 0 R (section*.6) 249 0 R (section*.60) 413 0 R (section*.61) 414 0 R (section*.62) 415 0 R 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